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http://dx.doi.org/10.9713/kcer.2017.55.3.313

Development of a Commercial Process for Micro-Encapsulation of Lactic Acid Bacteria Using Sodium Alginate  

Kim, Jiyeon (School of Energy, material & chemical engineering, Korea University of technology and education)
You, Seong-sik (School of Energy, material & chemical engineering, Korea University of technology and education)
Publication Information
Korean Chemical Engineering Research / v.55, no.3, 2017 , pp. 313-321 More about this Journal
Abstract
We aimed to develop commercialization process of encapsulation which is superior in productivity compared to existing methods by using sodium alginate. Also, in the same process, sodium alginate with chitosan was used to encapsulate lactic acid bacteria with the same process and then the viable cell counts of the two encapsulated lactic acid bacteria were compared. As a test result of the fluidized drying process developed by the present researchers, it was found that the drying time was shortened by 15 to 20 hours compared to the freeze drying method, but the number of viable lactic acid bacteria was about 75% as compared with freeze drying. However, considering the cost and time of drying, it can be confirmed that the commercialization process is possible by the fluidized bed drying method. When the number of viable cells of Ca-alginate capsule and Chitosan-alginate capsule were compared, it was confirmed that there were about $1{\times}10^9$ or more bacteria in the former and about $1{\times}10^3$ in the latter. The lactic acid bacterium capsules prepared by the present technique were stable for 96 hours or more at pH 4.65 and 6.01, but disappeared within 1 hour at pH 7.07 and 8.35. This suggests that the disintegration of lactic acid bacteria can be easily occurred in small and large intestine.
Keywords
Encapsulation; Lactic acid bacteria; Alginate; Fludized bed drying; Chitosan-alginate;
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Times Cited By KSCI : 1  (Citation Analysis)
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