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http://dx.doi.org/10.9713/kcer.2016.54.3.374

Method for Drying of Crude Extract Obtained by Biomass Extraction Using an Ionic Liquid  

Kim, Seul Ki (Department of Chemical Engineering, Kongju National University)
Kim, Jin-Hyun (Department of Chemical Engineering, Kongju National University)
Publication Information
Korean Chemical Engineering Research / v.54, no.3, 2016 , pp. 374-379 More about this Journal
Abstract
When using an ionic liquid as co-solvent, the extraction efficiency of anticancer agent paclitaxel from biomass was dramatically improved. However, the residual ionic liquid had a significant negative effect on convenient and feasibility of following concentration and drying steps. In this study, a novel method was developed for the effective drying of the crude extract obtained from biomass extraction with ionic liquid. The residual ionic liquid was easily and conveniently removed by drying alone after pre-treatment and additional washing of a sample with water. The optimal crude extract/water ratio and mixing time for pre-treatment and crude extract/water ratio for additional washing were 1:70 (w/v), 4 min, and 1:100 (w/v), respectively. In the microwave-assisted drying process, the drying time was 9-fold shorter than in the vacuum oven drying process.
Keywords
Paclitaxel; Extraction; Residual ionic liquid; Removal; Drying;
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Times Cited By KSCI : 4  (Citation Analysis)
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