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http://dx.doi.org/10.9713/kcer.2015.53.3.289

Functional Cosmetic Characteristics of Momordica charantia Fruit Extract  

Kim, Hyun-Woo (Department of Pharmaceutical Engineering, Inje University)
Shin, Hyejin (Department of Pharmaceutical Engineering, Inje University)
Hwang, Danbi (Department of Pharmaceutical Engineering, Inje University)
Lee, Jieun (Department of Pharmaceutical Engineering, Inje University)
Jeong, Hyangli (Department of Pharmaceutical Engineering, Inje University)
Kim, Donguk (Department of Pharmaceutical Engineering, Inje University)
Publication Information
Korean Chemical Engineering Research / v.53, no.3, 2015 , pp. 289-294 More about this Journal
Abstract
In this research, water and ethanol extract of Momordica charantia shells, fruits and seeds were tested to see possibility as natural functional cosmetic agent. Water and ethanol extract showed 69.45 mg/g and 70.87 mg/g polyphenol concentration, respectively. Momordica charantia water and ethanol extracts did not indicate cell toxicity up to $1,000{\mu}g/ml$ concentration in MTT assay. Tyrosinase inhibition effects of water and ethanol extract were lower than arbutin, however, ethanol extract showed better DOPA oxidation inhibition effect than arbutin. Elastase inhibition effects of ethanol extract displayed similar efficacy with adenosine at higher concentrations. Solution formulations (5% extract) were stable for 28 days in both extracts, however, lotion formulation (1% extract) showed considerable variation in viscosity whereas ethanol extraction indicated relative stability. In conclusion, water and ethanol extract of Momordica charantia shells, fruits and seeds indicated strong possibility for whitening and antiwrinkle functional cosmetic ingredient.
Keywords
Momordica charantia; Whitening; Anti-wrinkle; Safety; Stability;
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Times Cited By KSCI : 3  (Citation Analysis)
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