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http://dx.doi.org/10.9713/kcer.2013.51.5.575

Effect of Alcohols and Carboxylic Acids on Extraction Characteristics for 1,3-Propanediol by Aqueous Two Phases Systems  

Hong, Yeon Ki (Department of Chemical and Biological Engineering, Korea National University of Transportation)
Publication Information
Korean Chemical Engineering Research / v.51, no.5, 2013 , pp. 575-579 More about this Journal
Abstract
1,3-Propandiol is a promising chemical which can be produced from fermentation of glycerol because the application of 1,3-propanediol is mainly in the production of bio-polytrimethylene terephthalate (bio-PTT). However, the cost of downstream processes in the biological production of 1,3-propanediol can make a high portion in the total production cost due to the large amount of water and the by-produced carboxylic acids such as succinic, lactic and acetic acids in 1,3-propanediol fermentation broth. In this study, aqueous two-phases systems composed of hydrophilic alcohols and phosphate salts were applied to the recovery of 1,3-propanediol from its artificial aqueous solution. Formation of aqueous biphases in hydrophilic alcohols and phosphate salts was due to the salting-out effect of salts in bottom phase, thereby 1,3-propanediol in bottom phase was moved into top phase. Extraction efficiency for 1,3-propanediol was proportional to the polarity of hydrophilic alcohols and the basicity of salts and the maximum value of extraction efficiency was more than 98%. In the aqueous two-phases systems after extraction, there was no carboxylic acid in top phase. Therefore, it was concluded that the aqueous two-phases systems composed of hydrophilic alcohols and phosphate salts were effective for the selective recovery of 1,3-propanediol without any coextraction of carboxylic acids.
Keywords
1,3-Propanediol; Aqueous Two-phases; Carboxylic Acids; Salting-out;
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1 Jiang, B., Li, Z.-G., Dai, J.-Y., Zhang, D.-J. and Xiu, Z.-L., "Aqueous Two-Phase Extraction of 2,3-Butanediol from Fermentation Broths Using Ethanol/Phosphate System," Process Biochem., 44, 112-117(2009).   DOI   ScienceOn
2 Wu, R. C., Ren, H. J., Xu, Y. and Liu, D., "The Final Recover of Salt from 1,3-Propanediol Fermentation Broth," Sep. Purif. Technol., 73, 122-125(2010).   DOI   ScienceOn
3 Chen, Z., Liu, H. and Liu, D., "Regulation of 3-Hydroxypropionaldehyde Accumulation in Klebsiella Pneumoniae by Overexpression of dhaT and dhaD Genes," Enzyme Microb. Technol., 45, 305-309(2009).   DOI   ScienceOn
4 Mourao, T., Claudio, A. F. M., Boal-Palheiros, I., Freire, M. G., and Coutinho, J. A. P., "Evaluation of the Impact of Phosphate Salts on the Formation of Ionic-liquid Based Aqueous Biphasic Systems," J. Chem. Thermodyn., 54, 398-405(2012).   DOI   ScienceOn
5 Navapara, R. D., Avhad, D. N. and Rathod, V. K., "Application of Response Surface Methodology for Optimization of Bromelain Extraction in Aqueous Two-Phase System," Sep. Sci. Technol., 46, 1838-1847(2011).   DOI   ScienceOn
6 http://www.marketsandmarkets.com/Market-Reports/1-3-propanediolpdo-market-760.html.
7 Hong, Y. K., "Separation Processes of Biologically Produced 1,3-Propanediol," Korean Chem. Eng. Res.(HWAHAK KONGHAK), 50, 759-765(2012).   과학기술학회마을   DOI   ScienceOn
8 Kaur, G., Srivastava, A. K. and Chand, S., "Advanced in Biotechnological Production of 1,3-Propanediol," Biochem. Eng. J., 64, 106-118(2012).   DOI   ScienceOn
9 Lim, Z., Jiang, B., Zhang, D. and Xiu, Z., "Aqueous Two-Phase Extraction of 1,3-Propanediol from Glycerol-Based Fermentation," Sep. Purif. Technol., 66, 472-478(2009).   DOI   ScienceOn
10 Hao, J., Xu, F. and Liu, D., "Downstream Processing of Fermentation Broth," J. Chem. Technol. Biotechnol., 81, 102-108(2006).   DOI   ScienceOn
11 Wu, R. C., Xu, Y. Z., Song, Y. Q., Luo, J. A. and Liu, D., "A Novel Strategy for Salts Recovery from 1,3-Propanediol Fermentation Broth by Bipolar Membrane Electrodialysis," Sep. Purif. Technol., 83, 9-14(2011).   DOI   ScienceOn
12 Xiu, Z.-L. and Zeng, A.-P., "Present State and Perspective of Downstream Processing of Biologically Produced 1,3-Propanediol and 2,3-Butanediol," Appl. Microbiol. Biotechnol., 78, 917-926 (2008).   DOI   ScienceOn
13 Malinowski, J. J., "Reactive Extraction for Downstream Separation of 1,3-Propanediol," Biotechnol. Prog., 16, 76-79(2000).   DOI   ScienceOn