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http://dx.doi.org/10.9713/kcer.2013.51.3.403

Synthesis of Water-Dispersible Maghemite Nanocrystals using 6-Aminohexanoic Acid as a Capping Agent  

Yu, Taekyung (Department of Chemical Engineering, Kyung Hee University)
Publication Information
Korean Chemical Engineering Research / v.51, no.3, 2013 , pp. 403-406 More about this Journal
Abstract
This paper describes a simple route to synthesis of water-dispersible monodisperse maghemite (${\gamma}-Fe_2O_3$) nanocrystals using 6-aminohexanoic acid (AHA) as a stabilizer. The water-dispersible ${\gamma}-Fe_2O_3$ nanocrystals with an average size of 5 nm were obtained simply by addition of $Fe(CO)_5$ into an octyl ether solution containing AHA at $195^{\circ}C$ under argon condition. As-prepared AHA coated ${\gamma}-Fe_2O_3$ nanocrystals exhibited highly crystallinity and magnetic property while keeping a good dispersity in an aqueous phase. We also obtained water-dispersible AHA coated ${\gamma}-Fe_2O_3$ nanocrystals using ligand-exchange method, demonstrating that AHA can be a good candidate for preparing water-dispersible uniform metal oxide nanocrystals.
Keywords
Maghemite; Water-Dispersible; Nanocrystals; 6-aminohexanoic Acid; Ligand-Exchange;
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1 Park, J., Joo, J. Kwon, S. G., Jang, Y. and Hyeon, T., "Synthesis of Monodisperse Spherical Nanocrystals," Angew. Chem. Int. Ed., 46, 4630(2007).   DOI   ScienceOn
2 Hyeon, T., Lee, S. S., Park, J., Chung, Y. and Na, H. B., "Synthesis of Highly Crystalline and Monodisperse Maghemite Nanocrystallites without a Size-Selection Process," J. Am. Chem. Soc., 123, 12798(2001).   DOI   ScienceOn
3 Kim, S.-W., Kim, S., Tracy, J. B., Jasanoff, A. and Bawendi, M. G., "Phosphine Oxide Polymer for Water-Soluble Nanoparticles," J. Am. Chem. Soc., 127, 4556(2005).   DOI   ScienceOn
4 Pellegrino, T., Manna, L., Kudera, S., Liedl, T., Koltysh, D., Rogach, A. L., Keller, S., Radler, J., Natile, G. and Parak, W. J., "Hydrophobic Nanocrystals Coated with an Amphiphilic Polymer Shell: A General Route to Water Soluble Nanocrystals," Nano Lett., 4, 703(2004).   DOI   ScienceOn
5 Yi, D. K., Selvan, S. T., Lee, S. S., Papaefthymiou, G. C., Kundaliya, D. and Ying, J. Y., "Silica-Coated Nanocomposites of Magnetic Nanoparticles and Quantum Dots," J. Am. Chem. Soc., 127, 4990 (2005).   DOI   ScienceOn
6 Nikolic, M. S., Krack, M., Aleksandrovic, V., Kornowski, A., Forster, S. and Weller, H., "Tailor-Made Ligands for Biocompatible Nanoparticles," Angew. Chem. Int. Ed., 45, 6577(2006).   DOI   ScienceOn
7 Song, H.-T., Choi, J.-S., Huh, Y.-M., Kim, S., Jun, Y.-W., Suh, J.-S. and Cheon, J., "Surface Modulation of Magnetic Nanocrystals in the Development of Highly Efficient Magnetic Resonance Probes for Intracellular Labeling," J. Am. Chem. Soc., 127, 9992 (2005).   DOI   ScienceOn
8 Lee, N. and Hyeon, T., "Designed Synthesis of Uniformly Sized Iron Oxide Nanoparticles for Efficient Magnetic Resonance Imaging Contrast Agents," Chem. Soc. Rev., 41, 2575(2012).   DOI   ScienceOn
9 Lee, N., Choi, Y., Lee, Y., Park, M., Moon, W. K., Choi, S. H. and Hyeon, T., "Water-Dispersible Ferrimagnetic Iron Oxide Nanocubes with Extremely High r2 Relaxivity for Highly Sensitive in Vivo MRI of Tumors," Nano Lett., 12, 3127(2012).   DOI   ScienceOn
10 Na, H. B., Lee, J. H., An. K., Park, Y. I., Park, M., Lee, I. S., Nam, D.-H., Kim, S. T., Kim, S.-H., Kim, S.-W., Lim, K.-H., Kim, K.-S., Kim, S.-O. and Hyeon, T., "Development of a $T_{1}$ Contrast Agent for Magnetic Resonance Imaging Using MnO Nanoparticles," Angew. Chem. Int. Ed., 46, 5397(2007).   DOI   ScienceOn
11 Woo, K., Hong, J. Choi, S., Lee, H.-W., Ahn, J.-P., Kim, C. S. and Lee, S. W., "Easy Synthesis and Magnetic Properties of Iron Oxide Nanoparticles," Chem. Mater., 16, 2814(2004).   DOI   ScienceOn
12 Park, J., Lee, E., Hwang, N.-M., Kang, M., Kim, S. C., Hwang, Y., Park, J.-G., Noh, H.-J., Kim, J.-Y., Park, J.-H. and Hyeon, T., "One-Nanometer-Scale Size-Controlled Synthesis of Monodisperse Magnetic Iron Oxide Nanoparticles," Angew. Chem. Int. Ed., 44, 2872(2005).   DOI   ScienceOn
13 Li, Z., Chen, H., Bao, H. and Gao, M., "One-Pot Reaction to Synthesize Water-Soluble Magnetite Nanocrystals," Chem. Mater., 16, 1391(2004).   DOI   ScienceOn
14 Zeng, H., Li, J., Liu, J. P., Wang, Z. L. and Sun, S., "Exchange- Coupled Nanocomposite Magnets by Nanoparticle Self-Assembly," Nature 420, 395(2002).   DOI   ScienceOn
15 Hyeon, T., "Chemical Synthesis of Magnetic Nanoparticles," Chem. Commun., 927 (2003).
16 Katz, E. and Willner, I., "Integrated Nanoparticle-Biomolecule Hybrid Systems: Synthesis, Properties, and Applications," Angew. Chem. Int. Ed. 43, 6042(2004).   DOI   ScienceOn
17 Momet, S., Vasseur, S., Grasset, F. and Duguet, E., "Magnetic Nanoparticle Design for Medical Diagnosis and Therapy," J. Mater. Chem., 14, 2161(2004).   DOI   ScienceOn
18 Franke, M. E., Koplin, T. J. and Simon, U., "Metal and Metal Oxide Nanoparticles in Chemiresistors: Does the Nanoscale Matter?," Small., 2, 36(2006).   DOI   ScienceOn
19 Nam, J.-M., Thaxton, C. S. and Mirkin, C. A., "Nanoparticle-Based Bio-Bar Codes for the Ultrasensitive Detection of Proteins," Science, 301, 1884(2003).   DOI   ScienceOn
20 Jun, Y.-W., Huh, Y.-M., Choi, J.-S., Lee, J.-H., Song, H.-T., Kim, S., Yoon, S., Kim, K.-S., Shin, J.-S., Suh, J.-S. and Cheon, J., "Nanoscale Size Effect of Magnetic Nanocrystals and Their Utilization for Cancer Diagnosis via Magnetic Resonance Imaging," J. Am. Chem. Soc., 127, 5732(2005).   DOI   ScienceOn
21 Lu, A.-H., Salabas, E. L. and Schuth, F., "Magnetic Nanoparti-cles: Synthesis, Protection, Functionalization, and Application," Angew. Chem. Int. Ed., 46, 1222(2007).   DOI   ScienceOn