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Anti-acne and Anti-atopic Dermatitis Effect of Plant Extracts Including Eucommia ulmoides Oliv and Phellodendron amurense  

Kim, Gi Eun (Biometics)
Kim, Jin Hong (Biometics)
Hong, Seul Ki (Department of Pharmaceutical Engineering, Inje University)
Kim, Tagon (Department of Pharmaceutical Engineering, Inje University)
Kim, Donguk (Department of Pharmaceutical Engineering, Inje University)
Publication Information
Korean Chemical Engineering Research / v.48, no.6, 2010 , pp. 700-703 More about this Journal
Abstract
In this study, plant extracts including Eucommia ulmoides Oliv. and Phellodendron amurense were studied to test possible application for cosmetics and skin related medicine. Anti-oxidation effect of plant extracts was measured by DPPH free radical scavenging activity and it was insignificant at low concentration, however, it was as good as vitamin C, excellent anti-oxidation agent, at $1000{\mu}g/ml$. Anti-bacterial effect was tested by disc diffusion method, and plant extracts showed mild anti-bacterial effect for normal skin flora, Staphylococcus epidermidis while it indicated strong anti-bacterial effect for acne inducing Propionibacterium acne. Therefore it had powerful potential for anti-acne material because of selectivity. Anti-atopic dermatitis effect was tested by hairless mouse and plant extracts recovered damaged skin to near normal condition after 14 days of treatment. IgE concentration in treated mouse was decreased 16% compared with control. From the research, plant extracts indicated strong anti-acne and anti-atopic dermatitis effect, and showed strong potential for cosmetics and skin related medicine.
Keywords
Eucommia ulmoides Oliv; Phellodendron amurense; Plant Extracts; Anti-acne; Anti-atopic Dermatitis;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
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