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Anti-oxidation and Anti-atopic Dermatitis Effect of Herbal Wood Vinegar  

Kim, Tagon (Department of Pharmaceutical Engineering, Inje University)
Nho, Hwa Jung (Department of Pharmaceutical Engineering, Inje University)
Jun, Sang Hui (Department of Pharmaceutical Engineering, Inje University)
Kim, Kang Bae (Nollan Bio)
Kim, Donguk (Department of Pharmaceutical Engineering, Inje University)
Publication Information
Korean Chemical Engineering Research / v.48, no.6, 2010 , pp. 690-694 More about this Journal
Abstract
In this study, herbal wood vinegar including Bambusoideae, Cinnamomi Cortex, Zingiberis Rhizoma was tested to see possibility for cosmetic or skin related medicine. Anti-oxidation effect of herbal wood vinegar was tested by DPPH free radical scavenging activity, and showed 97% inhibition rate at $50{\mu}g/ml$. Anti-bacterial effect was tested by disc diffusion method, and it indicated strong anti-bacterial activity against normal skin flora Staphylococcus aureus. Whitening effect was measured by tyrosinase inhibition assay, and it was lower compared with vitamin C. Stability test was done by MTT assay, and cell toxicity was relatively high. Stability was also checked, and there was not significant change in color, aroma, appearance and pH during storage. Anti-atopic dermatitis test was done by hairless mouse and herbal wood vinegar recovered damaged skin to almost normal condition after 9 days of application. IgE concentration in herbal wood vinegar treated mouse was also reduced 30% compared with control. From the study, herbal wood vinegar showed good anti-oxidation, anti-bacterial and anti-atopic dermatitis effect, and had promising application in cosmetic or skin related medicine.
Keywords
Herbal Wood Vinegar; Anti-Oxidation; Antibiotic; Anti-Atopic Dermatitis; Safety;
Citations & Related Records
Times Cited By KSCI : 6  (Citation Analysis)
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