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Measurements and Modeling of the Activity Coefficients and Solubilities of L-alanine in Aqueous Electrolyte Solutions  

Lee, Bong-Seop (Department of Chemical Engineering, Kangwon National University)
Kim, Ki-Chang (Department of Chemical Engineering, Kangwon National University)
Publication Information
Korean Chemical Engineering Research / v.48, no.4, 2010 , pp. 519-533 More about this Journal
Abstract
Activity oefficients and solubilities of L-Alanine in aqueous solutions containing each of four electrolytes(NaCl, KCl, $NaNO_3$ and $KNO_3$) were measured at 298.15 K. The measurements of activity coefficients were carried out in the electrochemical cell coupled with two ion-selective electrodes(cation and anion), and the solubilities were measured by the gravimetric analysis of saturated solutions in equilibrium with the solid phase of L-alanine. To model the activity coefficients and solubilities of amino acid in the amino acid/electrolyte aqueous solutions, thermodynamic relations of the residual Helmholtz free energy in the amino acid/electrolyte aqueous solutions were developed based on the perturbed-chain statistical associating fluid theory(PC-SAFT) combined with the primitive mean spherical approximation(primitive-MSA). In the present model, it is assumed that the zwitterions of L-alanine are associated with each other and cross-associated with water molecules, and also cross-associated with the cation and anion dissociated from an electrolyte(inorganic salt). The activity coefficients and solubilities of L-Alanine calculated from the theoretical model proposed in this work are found to be well agreeable with experimental data.
Keywords
Electrolyte; Amino Acid; Activity Coefficients; Solublities; PC-SAFT; Primitive-MSA;
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Times Cited By KSCI : 2  (Citation Analysis)
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