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Cosmetic Effect of Angelica gigas Nakai Root Extracts  

Park, Suk Kyoung (Coreana Cosmetics)
Hong, Seul-Ki (Biometics, Inje University)
Kim, Hee Jin (SYNOPEX)
Kim, Bo Young (Department of Pharmaceutical Engineering, Inje University)
Kim, Tagon (Department of Pharmaceutical Engineering, Inje University)
Kang, Jae Seon (Department of Pharmacy, Kyungsung University)
Kim, Donguk (Department of Pharmaceutical Engineering, Inje University)
Publication Information
Korean Chemical Engineering Research / v.47, no.5, 2009 , pp. 553-557 More about this Journal
Abstract
Root extracts of Angelica gigas Nakai were tested to see the possibility for functional cosmetic agents. From ethanol extraction method, 97% of decursin and decursinol angelate was obtained, and concentration ratio of decursin to decursinol angelate was about 3:2. To test possibility as a functional cosmetic agent, DPPH free radical scavenging assay, UVA/B absorption, tyrosinase inhibition assay, melanogenesis inhibition assay, elastase inhibition assay and MTT assay were done. Root extracts of Angelica gigas Nakai showed $45.2{\pm}3.9%$ tyrosinase inhibition of tyrosine, and $24.2{\pm}12.0%$ melanin inhibition at $15{\mu}g/ml$ extract concentration, so that it indicated good whitening effect. DPPH free radical scavenging activity was $40.9{\pm}9.1%$ at $240{\mu}g/ml$ concentration, which is relatively good. Anti-wrinkle effect was poor such that it was $12.7{\pm}6.8%$ at $100{\mu}g/ml$. UVA/B absorption was also negligible. From the research, root extracts of Angelica gigas Nakai showed good potential as a whitening agent.
Keywords
Angelica Gigas Nakai; Decursin; Antioxidation; Whitening; Anti-Wrinkle;
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Times Cited By KSCI : 4  (Citation Analysis)
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