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Solvent Extraction of Tanshinone IIA from Salvia Miltiorrhiza Bunge  

Wan, Xiaolong (Center for Advanced Bioseparation Technology, Department of Chemical Engineering, Inha University)
Jung, Yong An (Chemical Analysis & Research Team, Korea Machinery-Meter and Petrochemical Testing & Research Institute)
Row, Kyung Ho (Center for Advanced Bioseparation Technology, Department of Chemical Engineering, Inha University)
Publication Information
Korean Chemical Engineering Research / v.46, no.4, 2008 , pp. 660-664 More about this Journal
Abstract
In this work, analytical HPLC was utilized to obtain Tanshinone IIA (TIIA) from Salvia Miltiorrhiza Bunge (SMB). The optimum operating conditions were experimentally determined to analyze the TIIA in the pretreated extract. SMB was extracted with the various organic solvents of methanol, ethyl acetate, and ethanol, then the extract was analyzed to compare the amount of TIIA. From the results, the methanol showed the best extraction efficiency of TIIAd. The analysis by $C_{18}$ column was performed. The mobile phase was composed of methanol and water, and the isocratic elution mode was mainly applied. $2.154{\mu}g$ of TIIA/mg of SMB powder was extracted with methanol.
Keywords
Salvia Miltiorrhiza Bunge; Tanshinone IIA; Extraction; Purification; RP-HPLC;
Citations & Related Records
Times Cited By KSCI : 3  (Citation Analysis)
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