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http://dx.doi.org/10.13045/jar.2020.00227

A Study of the Initial Dose of Sweet Bee Venom for the Treatment of Patients with Lower Back Pain  

Lee, Kwang Ho (Department of Acupuncture and Moxibustion Medicine, College of Korean Medicine, Sangji University)
Publication Information
Journal of Acupuncture Research / v.37, no.3, 2020 , pp. 173-176 More about this Journal
Abstract
Sweet bee venom (SBV) causes less hypersensitivity reactions compared with whole bee venom. To determine the appropriate SBV initial dose for pharmacopuncture treatment of lower back pain, the initial dose, and the dose which caused hypersensitivity were retrospectively reviewed between January 1st, 2017 and December 31st, 2019. There were 523 first-visit patients who received SBV pharmacopuncture for lower back pain and 41 showed hypersensitivity. No systemic reactions were observed and localized reactions were not severe. Hypersensitivity was observed during the first (7 cases), and fifth treatments (8 cases). An initial SBV (10%) volume of 0.1 mL was used in 2 cases, 0.2 mL in 6 cases, 0.6 mL in 41 cases, and 1.2 mL in 474 cases. The hypersensitivity rate during the first and fifth treatment was 1.34% and 1.53%, respectively. As a result, 1.2 mL of SBV was considered the acceptable initial dose. However, for safer treatment, we recommend limiting the initial dose of SBV to 0.5 mL.
Keywords
allergy; anaphylaxis; bee venom; pharmacopuncture; hypersensitivity;
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Times Cited By KSCI : 4  (Citation Analysis)
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