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http://dx.doi.org/10.13045/acupunct.2015058

A Study on the Correlation between Pain Intensity and HbA1c for Diabetic Peripheral Neuropathy Patients  

Jung, Se Ho (Department of Acupuncture & Moxibustion Medicine, Chungju Hospital of Traditional Korean Medicine, Semyung University)
Sung, Hee Jin (Department of Acupuncture & Moxibustion Medicine, Chungju Hospital of Traditional Korean Medicine, Semyung University)
Lim, Su Ji (Department of Acupuncture & Moxibustion Medicine, Chungju Hospital of Traditional Korean Medicine, Semyung University)
Lee, Cham Kyul (Department of Acupuncture & Moxibustion Medicine, Chungju Hospital of Traditional Korean Medicine, Semyung University)
Jo, Na Young (Department of Acupuncture & Moxibustion Medicine, Jecheon Hospital of Traditional Korean Medicine, Semyung University)
Roh, Jeong Du (Department of Acupuncture & Moxibustion Medicine, Jecheon Hospital of Traditional Korean Medicine, Semyung University)
Lee, Eun Yong (Department of Acupuncture & Moxibustion Medicine, Chungju Hospital of Traditional Korean Medicine, Semyung University)
Publication Information
Journal of Acupuncture Research / v.32, no.4, 2015 , pp. 17-27 More about this Journal
Abstract
Objectives : The purpose of this study is to evaluate the correlation between HbA1c and pain intensity in diabetic peripheral neuropathy patients, and to compare the difference between two groups divided by the risk of complications. Methods : The participants were 46 men and women suffering from neuropathic pain diagnosed with diabetes mellitus who visited the Hospital of Traditional Korean Medicine, Semyung University from June, 2014 to August, 2015. Age, duration of diabetes mellitus, numeric rating scale(NRS), and Michigan neuropathy screening instrument(MNSI) were used as evaluation tools. Results : 1. In all 46 cases, there were no significant correlations between HbA1c and age, duration of diabetes mellitus, NRS, MNSIQ, or MNSIE. 2. Among 23 cases with a high risk of complications (more than 7.0 % of HbA1c, group A), there were no significant correlations between HbA1c and age, duration of diabetes mellitus, NRS, MNSIQ, or MNSIE. 3. Among 23 cases with a low risk of complications(less than 7.0 % of HbA1c, group B), there were no significant correlations between HbA1c and age, duration of diabetes mellitus, NRS, MNSIQ, or MNSIE. 4. Means of duration of diabetes mellitus, NRS, MNSIQ, and MNSIE were higher in group A than group B, but there were no significant correlations in statistics. Conclusions : This study could not find statistically significant correlations between pain intensity and HbA1c in diabetic peripheral neuropathy patients, so more studies are required in the future.
Keywords
Diabetic Peripheral Neuropathy; Correlation; NRS; MNSI; HbA1c;
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Times Cited By KSCI : 3  (Citation Analysis)
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1 Asociety for the research of Neuropathy in Korean Diabetes Association. Clinical Practice of Diabetic Neuropathy. 2nd ed. Seoul : Korean Diabetes Association. 2007 : 1-48.
2 Dyck PJ, Kratz KM, Karnes JL et al.The Prevalence by Staged Severity of Various Types of Diabetic Neuropathy, Retinopathy, and Nephropathyina Population-based Cohort : The Rochester Diabetic Neuropathy Study. Neurology. 1993 ; 43(4) : 817-24.   DOI
3 Kim SS, Won JC, Kwon HS et al. Prevalence and Clinical Implications of Painful Diabetic Peripheral Neuropathy in Type 2 Diabetes :Results from a Nationwide Hospital-based Study of Diabetic Neuropathy in Korea. Diabetes Res Clin Pract. 2014 ; 103(3) : 522-9.   DOI
4 Boulton AJ, Gries FA, Jervell JA. Guidelines for the Diagnosis and Outpatient Management of Diabetic Peripheral Neuropathy. Diabet Med. 1998 ; 15(6) : 508-14.   DOI
5 Ziegler D, Nowak H, Kempler P, Vargha P, Low PA.Treatment of Symptomatic Diabetic Polyneuropathy with the Antioxidant Alpha-lipoic Acid : A Meta-analysis. Diabet Med. 2004 ; 21(2) : 114-21.   DOI
6 Keen H, Payan J, Allawi J et al. Treatment of Diabetic Neuropathy with Gamma-Linolenic Acid. The Gamma-Linolenic Acid Multicenter Trial Group. Diabetes Care. 1993 ; 16(1) : 8-15.   DOI
7 Jeon EJ, Kwon HJ, Shin IH, Jung ED, Kang SB, Shon HS. Efficacy of Saam Acupuncture for Diabetic Peripheral Neuropathy-A Pilot, Randomized Controlled Study. Korean J Acupunct. 2013 ; 30(4) : 289-97.   DOI
8 Kwon YK, Choi KR, Lee JS et al. Two Cases of Diabetic Peripheral Polyneuropathy Improved by Bogan-tang. J Korean Oriental Med.2002; 23(1) : 170-6.
9 Park SK, Kwon EH, Shin HC, Kang SB. One Case of Diabetic Peripheral Polyneuropathy Improved by Binsosan-gamibang. Korean J. Orient. Int. Med. 2005 ; 26(4) : 935-40.
10 Yang YS. Effect of Serum HbA1c and Duration of Diabetes Mellitus on Diabetic Peripheral Neuropathy [dissertation]. Gwangju : Chonnam National Univ. 2000. Korean.
11 UK Prospective Diabetes Study (UKPDS) Group. Intensive Blood-Glucose Control with Sulphonylureas or Insulin Compared with Conventional Treatment and Risk of Complications in Patients with Type 2 Diabetes (UKPDS 33). Lancet. 1998 ; 352(9131) : 837-53.   DOI
12 Morley S, Pallin V. Scaling the Affective Domainof Pain : A Study of the Dimensionality of Verbal Descriptors. Pain. 1995 ; 62(1) : 39-49.   DOI
13 Feldman EL, Stevens MJ, Thomas PK, Brown MB, Canal N, Greene DA. A Practical Two- step Quantitative Clinical and Electrophysiological Assessment for the Diagnosis and Staging of Diabetic Neuropathy. Diabetes Care. 1994 ; 17(11) : 1281-9.   DOI
14 Ross MA. Neuropathies Associated with Diabetes. Med Clin North Am. 1993 ; 77(1) : 111-24.   DOI
15 Halat KM, Dennehy CE. Botanicals and Dietary Supplements in Diabetic Peripheral Neuropathy. J Am Board Fam Pract. 2003 ; 16(1) : 47-57.   DOI
16 Kim JM, Youn SS, An SH et al. Overview of Diabetic Peripheral Neuropathy and Need for Therapeutic Strategyusing Traditional Korean Medicine. J Korean Oriental Med. 2009 ; 30(5) : 127-36.
17 Chun SW, Ko KS. Summary of the Update to the Diabetic Neuropathy Management Guidebook. J Korean Diabetes. 2012 ; 13(3) : 115-23.   DOI
18 Kang MS, Kim CH. Management of Diabetic Peripheral Neuropathy. Korean J Med. 2015 ; 89(3) : 277-81.   DOI
19 Doo HK. Internal Medicine of Kidney in Oriental Medicine. Seoul : Institute of Oriental Medicine. 1991 : 969-76.
20 International Expert Committee. International Expert Committee Report on the Role of the A1C Assay in the Diagnosis of Diabetes. Diabetes Care. 2009 ; 32(7) : 1327-34.   DOI
21 Holman RR, Paul SK, Bethel MA, Matthews DR, Neil HA. 10-year Follow-up of Intensive Glucose Control in Type 2 Diabetes. N Engl J Med. 2008 ; 359(15) : 1577-89.   DOI
22 Wall PD, Melzack R. Textbook of Pain. Seoul : Jungdam. 2002 : 483-4.
23 Lunetta M, Le Moli R, Grasso G, Sangiorgio L. A Simplified Diagnostic Test for Ambulatory Screening of Peripheral Diabetic Neuropathy. Diabetes Res Clin Pract. 1998 ; 39(3) : 165-72.   DOI
24 Booya F, Bandarian F, Larijani B, Pajouhi M, Nooraei M, Lotfi J. Potential Risk Factors for Diabetic Neuropathy : A Case Control Study. BMC Neurol. 2005 ; 5 : 24.   DOI
25 Moghtaderi A, Bakhshipour A, Rashidi H. Validation of Michigan Neuropathy Screening Instrument for Diabetic Peripheral Neuropathy. Clin Neurol Neurosurg. 2006 ; 108(5) : 477-81.   DOI
26 Herman WH, Pop-Busui R, Braffett BH et al. Use of the Michigan Neuropathy Screening Instrument as a Measure of Distal Symmetrical Peripheral Neuropathyin Type 1 Diabetes : Results from the Diabetes Control and Complications Trial/Epidemiology of Diabetes Inter ventionsand Complications. Diabet Med. 2012; 29(7) : 937-44.   DOI
27 Choi HY, Do HJ, Oh SW et al. The Validity of Michigan Neuropathy Screening Instrument as a Screening Test and Risk Factors for Diabetic Peripheral Neuropathy. J Korean Acad Fam Med. 2007 ; 28(8) : 610-5.