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http://dx.doi.org/10.13045/acupunct.2014051

The Effects of Sterilization on Jakyakgamcho Decoction(Shaoyaogancao Decoction) Pharmacopuncture: an Investigation to Minimize Loss of Principal Components  

Lee, Jong Hwan (Department of Acupuncture and Moxibustion Medicine, Gang-Nam Jaseng Oriental Medicine Hospital)
Jun, Jae Yun (Department of Acupuncture and Moxibustion Medicine, Gang-Nam Jaseng Oriental Medicine Hospital)
Lim, Su Jin (Department of Acupuncture and Moxibustion Medicine, Gang-Nam Jaseng Oriental Medicine Hospital)
Kim, Hae Sol (Department of Acupuncture and Moxibustion Medicine, Gang-Nam Jaseng Oriental Medicine Hospital)
Kim, Ho Sun (Department of Acupuncture and Moxibustion Medicine, Gang-Nam Jaseng Oriental Medicine Hospital)
Bae, Young Hyeon (Department of Acupuncture and Moxibustion Medicine, Gang-Nam Jaseng Oriental Medicine Hospital)
Lee, In Hee (R&D Center, Gang-Nam Jaseng Oriental Medicine Hospital)
Kim, Min Jeong (R&D Center, Gang-Nam Jaseng Oriental Medicine Hospital)
Kim, Eun Jee (R&D Center, Gang-Nam Jaseng Oriental Medicine Hospital)
Ha, In Hyuk (Department of Rehabilitation Medicine, Gang-Nam Jaseng Oriental Medicine Hospital)
Lee, Jin Ho (Department of Rehabilitation Medicine, Gang-Nam Jaseng Oriental Medicine Hospital)
Lee, Jae Woong (R&D Center, Gang-Nam Jaseng Oriental Medicine Hospital)
Publication Information
Journal of Acupuncture Research / v.31, no.4, 2014 , pp. 29-32 More about this Journal
Abstract
Objectives : Jakyakgamcho decoction is a traditional prescription known to be an effective pain control medication and muscle relaxant. For more localized treatment outcomes achieved in a shorter period of time, Jakyakgamcho decoction was reprocessed into a form of pharmacopuncture. An analysis of Jakyakgamcho decoction pharmacopuncture showed that there was a significant loss of paeoniflorin(Jakyak's index component). This study was designed to investigate ways to minimize this loss. Methods : After making changes to the processing methods of Jakyakgamcho decoction pharmacopuncture, we measured the quantity of paeoniflorin using high performance liquid chromatography(HPLC) for a before-and-after analysis Results : Paeoniflorin loss was observed 15 minutes after sterilization with $Na_2HPO_4$ at $121^{\circ}C$ Conclusions : It was found that paeoniflorin loss did not occur when pH was not controlled for during processing.
Keywords
Jakyak; Gamcho; Jakyakgamcho decoction pharmacopuncture; Paeoniflorin;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
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