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http://dx.doi.org/10.9799/ksfan.2017.30.2.251

Fatty Acid Composition and Anti-inflammatory Effects of the Freeze Dried Tenebrio molitor Larva  

Kang, Mi-Sook (Dept. of Alternative Medicine, Kyonggi University)
Kim, Min Ju (Dept. of Alternative Medicine, Kyonggi University)
Han, Jung-Soon (The Graduate School of Alternative Medicine, Kyonggi University)
Kim, Ae-Jung (The Graduate School of Alternative Medicine, Kyonggi University)
Publication Information
The Korean Journal of Food And Nutrition / v.30, no.2, 2017 , pp. 251-256 More about this Journal
Abstract
This study aimed to assess fatty acid composition and anti-inflammatory effects, such as nitric oxide(NO) production, expression of $TNF-{\alpha}$ and interleukin-6(IL-6), of Tenebrio molitor larva using RAW 264.7 cells. The content of total fatty acid in Tenebrio molitor larva was 76.14%, which was composed of oleic acid(42.12%), linoleic acid(32.67%) etc. There was no cytotoxicity at a dose level of 0.1, 1.0, 10, and $100{\mu}g/mL$ of freeze dried Tenebrio molitor larva ethanol extract(FDTEtOH) on RAW 264.7 cells. FDTEtOH significantly decreased NO production in LPS(lipopolysaccharide)-stimulated RAW 264.7 cells in a dose-dependent manner. Also, FDTEtOH dose-dependently suppressed the expression of $TNF-{\alpha}$ and IL-6. Thus, these results showed that Tenebrio molitor larva has the potential to be used as an anti-inflammatory food to improve immunity.
Keywords
Tenebrio molitor larva; fatty acid composition; anti-inflammatory effects;
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