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http://dx.doi.org/10.9799/ksfan.2016.29.3.307

Effects of Non-Alcoholic Fatty Liver in Rats by Acer tagmentosum Maxim. Extract  

Seo, Yoonhee (Dept. of Biology, Chungbuk National University)
Lee, Sang-Hwa (Bio Organic Material & Food Center, Seowon University)
Hwang, Hyung Seo (Dept. of Integrated Oriental Medical Bioscience, Semyung University)
Choe, Soo Young (Dept. of Biology, Chungbuk National University)
Publication Information
The Korean Journal of Food And Nutrition / v.29, no.3, 2016 , pp. 307-312 More about this Journal
Abstract
This study was performed to investigate the effects of Acer tegmentosum Maxim. extract (ATE) on non-alcoholic fatty liver in Sprague Dawley (SD) rats. During oral administration of ATE, non-alcoholic fatty liver was induced by treatment with DL-ethionine. The lipid, total cholesterol (T-CHO) and malondialdehyde (MDA) in the liver tissue of ATE-fed rats showed lower levels, as compared to ATE-unfed rats. In ATE-fed rats, the serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and ${\gamma}$-glutamyl transferase (GGT) were lower than the case of ATE-unfed rats. Oil red staining of the liver showed that the lipid deposits were decreased by feeding ATE. These results strongly indicated that ATE has positive effects of protection against non-alcoholic fatty liver formation.
Keywords
Acer tegmentosum Maxim. extract (ATE); non-alcoholic fatty liver disease (NAFLD); DL-ethionine;
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Times Cited By KSCI : 2  (Citation Analysis)
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