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http://dx.doi.org/10.9799/ksfan.2015.28.2.320

Antioxidant Activity of Rosa rugosa Thunberg and Effect on Serum Lipid Level in High Fat Diet-induced Mice  

Choi, Kyung-Soon (Dept. of Food and Nutrition, Sahmyook University)
Kim, Yong-Hwan (Dept. of Food Science & Biotechnology, Kyonggi University)
Lee, Ki-Won (The Research Institute of Basic Science, Kyonggi University)
Shin, Kyung-Ok (Dept. of Food and Nutrition, Sahmyook University)
Publication Information
The Korean Journal of Food And Nutrition / v.28, no.2, 2015 , pp. 320-327 More about this Journal
Abstract
Since Korean ancient times, powder of Rosa rugosa Thunberg has been used as a folk remedy. This study was conducted to verify the effects of Rosa rugosa Thunberg powder on in vitro antioxidant properties and serum lipid levels of high-fat diet-induced mice from a nutritional viewpoint. In the case of Rosa rugosa Thunberg powders, measurement of TPC, ABTS radical scavenging activity of trolox, DPPH radical scavenging activity, and measured value of FRAP were higher in ethanol extract than water extracts. For LDL-cholesterol concentration, mice fed 10% powder of Rosa rugosa Thunberg with high-fat diets showed a high numerical value compared with other groups (p<0.05). When testing for triglyceride concentrations in blood, mice fed 10% and 20% powder of Rosa rugosa Thunberg with high-fat diets showed the lowest numerical values (p<0.05). When testing for blood insulin concentrations, the high-fat diet group showed higher levels than compared to the control group (p<0.05). When testing for blood leptin concentrations, the high-fat diet group was $5.88{\pm}3.53ng/dL$, whereas mice fed 10% powder of Rosa rugosa Thunberg with high-fat diets showed a blood leptin level of $10.36{\pm}5.96ng/dL$ (p<0.05). Therefore, results prove that powder of Rosa rugosa Thunberg reduces triglyceride concentrations in the blood, and could be used as an excellent natural antioxidant in the future.
Keywords
Rosa rugosa Thunberg; antioxidant; triglyceride; insulin; leptin;
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