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http://dx.doi.org/10.9799/ksfan.2014.27.2.225

Effects of Soy Hydrolysate Fractions on Appetite Suppression and Ghrelin Releasing in ICR Mice  

Jung, Eun Young (Dept. of Home Economic Education, Jeonju University)
Suh, Hyung Joo (Dept. of Food and Nutrition, Korea University)
Publication Information
The Korean Journal of Food And Nutrition / v.27, no.2, 2014 , pp. 225-230 More about this Journal
Abstract
The objective of this study was to investigate the effects of soy hydrolysate fractions on appetite suppression and ghrelin releasing. In a short-term experiment, the cumulative food intake and serum ghrelin level were decreased significantly (p<0.05) during a 4-hr period after the interperitoneal injection of soy hydrolysate fractions (0.5, 1 g/kg BW), following a 12-hr period of food deprivation. In a long-term experiment, food efficiency ratio (FER) was also reduced significantly (p<0.05), when soy hydrolysate fractions (0.5, 1% in drinking water) were given orally for 8 wks. Therefore, we found that soy hydrolysate fractions affected food intake through appetite and ghrelin releasing in short-term and long-term experiments. In conclusion, this study indicated that soy hydrolysate fractions would diminish the sensation of hunger by reducing the secretion of orexigenic factors such as ghrelin that send satiety signals to the brain, terminating food intake.
Keywords
soy hydrolysate; appetite; food intake; ghrelin;
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