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Antioxidant and Antibacterial Activities of Ethyl Acetate Extract from Scutellaria baicalensis  

Kim, Yong-Hyun (Dept. of Biology, College of Natural Science, Soonchunhyang University)
Paek, Jong-Yoon (Dept. of Biology, College of Natural Science, Soonchunhyang University)
Kwon, Hyun-Jung (Dept. of Biology, College of Natural Science, Soonchunhyang University)
Lee, Jae-Woo (Dept. of Food Nutrition, Gimcheon College)
Yoon, Ok-Hyun (Dept. of Food Nutrition, Gimcheon College)
Han, Man-Deuk (Dept. of Biology, College of Natural Science, Soonchunhyang University)
Publication Information
The Korean Journal of Food And Nutrition / v.22, no.3, 2009 , pp. 367-376 More about this Journal
Abstract
This study aimed to determine the antioxidant and antibacterial effects of solvent extracts from Scutellaria baicalensis. The S. baicalensis was successively extracted with 5 kinds of solvents. The obtained samples were as follows; hexan fraction (IPK-1), chloroform fraction(IPK-2), ethyl acetate fraction(IPK-3), butanol fraction(IPK-4), and water fraction(IPK-5). These extracts were determined to process antibacterial effects using a paper disc method against 18 species of human pathogenic bacteria, antioxidant activity using 1,1-diphenyl-2-picrylhydrazyl(DPPH) method and inhibiting ability of linoleic acid autoxidation. Extracts of S. baicalensis has shown selective antibacterial effects on various strains of bacteria. Ethyl acetate fraction(IPK-3) showed the highest antimicrobial activity against selective bacteria, such as Staphylococcus aureus 285, S. aureus 503. In antioxidant activity test, free radical scavenger activity of IPK-3 fraction was 92% compared with BHA at the same concentration, while lipid peroxidation inhibition was 48%. These results suggest that IPK-3 fraction of S. baicalensis could be suitable in development of antimicrobial and antioxidant agents.
Keywords
Scutellaria baicalensis; antioxidant activity; antibacterial activity; ethyl acetate extract;
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Times Cited By KSCI : 12  (Citation Analysis)
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