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http://dx.doi.org/10.11626/KJEB.2018.36.3.385

Toxic Assessment of BDE-47 and BDE-209 using the Population Growth Rates of Skeletonema costatum  

Heo, Seung (West Sea Fisheries Research Institute, NIFS)
Lee, Ju-Wook (West Sea Fisheries Research Institute, NIFS)
Park, Yun-Ho (West Sea Fisheries Research Institute, NIFS)
Park, Na-Young (West Sea Fisheries Research Institute, NIFS)
Lee, In-Seok (Marine Environment Research Division, NIFS)
Hwang, Un-Ki (West Sea Fisheries Research Institute, NIFS)
Choi, Hoon (West Sea Fisheries Research Institute, NIFS)
Publication Information
Korean Journal of Environmental Biology / v.36, no.3, 2018 , pp. 385-391 More about this Journal
Abstract
Toxic assessment of PBDEs (BDE-47, BDE-209) has carried out using the rates of population growth in marine phytoplankton, Skeletonema costatum. The population growth rate (r) in S. costatum was determined after 96 hours of exposure to BDE-47 (2,2'4,4'-Tetrabromodiphenyl ether) and BDE-209 (2,2', 4,4'-Decabromodiphenyl ether). It was observed that r-value in the controls (absence PBDEs) was greater than 0.04 and further a decrease was observed in a dose-dependent manner. BDE-47 reduced population growth rate in a dose-dependent manner and a significant reduction occurred at a concentration greater than $0.31mgL^{-1}$, but BDE-209 had no effect on population growth rate even at concentrations greater than $125mgL^{-1}$. The population growth rate in the presence of BDE-47 and BDE-209, $EC_{50}$ values were $0.55mgL^{-1}$ and >$125mgL^{-1}$, and NOEC values were $0.16mgL^{-1}$ and >$125mgL^{-1}$, respectively. Therefore, BDE-47 is considered to be about over 80 times more harmful than BDE-209. In this study, the ecotoxic assessment based on population growth rate in S. costatum can be used as a baseline data for establishment of environment standard quality of BDE-47 and BDE-209 in the marine environment.
Keywords
PBDEs; BDE-47; BDE-209; Skeletonema costatum;
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1 Hwang UK, HM Ryu, JW Lee, SM Lee and HS Kang. 2014. Toxic effects of heavy metal (Cd, Cu, Zn) on population growth rate of the marine diatom (Skeletonema costatum). Korean J. Environ. Biol. 32:243-249.
2 ISO. 1995. ISO 10253: Water quality-marine algal growth inhibition test with Skeletonema costatum and Phaeodactylum tricornutum. The International Organization for Standardization. p. 7.
3 Bezares-Cruz J, CT Jafvert and I Hua. 2004. Solar photodecomposition of decabromodiphenyl ether: Products and quantum yield. Environ. Sci. Technol. 38:4149-4156.
4 Lebeuf M, CM Couillard, B Legare and S Trottier. 2006. Effects of De-BDE and PCB-126 on hepatic concentrations of PBDEs and methoxy-PBDEs in Atlantic tomcod. Environ. Sci. Technol. 40:3211-3216.
5 Lema SC, I Schultz, N Scholz, J Incardona and P Swanson. 2007. Neural defects and cardiac arrhythmia in fish larvae following embryonic exposure to 2,2ʹ,4,4ʹ-tetrabromodiphenyl ether(PBDE-47). Aquat. Toxicol. 82:296-307.
6 Martin M, PK Lam and BJ Richardson. 2004. An Asian quandary: where have all of the PBDEs gone? Mar. Pollut. Bull. 49:375-382.
7 McDonald TA. 2002. A perspective on the potential health risks of PBDEs. Chemosphere 46:745-755.
8 Okumura Y, J Koyama, H Takaku and H Satoh. 2001. Influence of organic solvents on the growth of marine microalgae. Arch. Environ. Contam. Toxicol. 41:123-128.
9 Rahman F, KH Langford, MD Scrimshaw and JN Lester, 2001. Polybrominated diphenyl ether (PBDE) flame retardants. Sci. Total Environ. 275:1-17.
10 Stapleton HM, RJ Letcher, J Li and JE Baker. 2009. Dietary accumulation and metabolism of polybrominated diphenyl ethers by juvenile carp (Cyprinus carpio). Environ. Toxicol. Chem. 23:1939-1946.
11 Usenko CY, EM Robinson, S Usenko, BW Brooks and ED Bruce. 2011. PBDE developmental effects on embryonic zebrafish. Environ. Toxicol. Chem. 30:1865-1872.
12 Vigano L, C Roscioli and L Guzzella. 2011. Decabromodiphenyl ether (BDE-209) enters the food web of the River Po and is metabolically debrominated in resident cyprinid fishes. Sci. Total Environ. 409:4966-4972.
13 We SU, CH Yoon and BY Min. 2010. Spatial distribution and residual consistency assessment of PBDEs in the surface sediment of the Masan Bay. Environ. Eng. Res. 32:427-436.
14 Zegers BN, WE Lewis, B Kees, RH Smittenberg, W Boer, JD Boer and JP Boon. 2003. Levels of polybrominated diphenyl ether flame retardants in sediment cores from western Europe. Environ. Sci. Technol. 37:3803-3807.
15 Baek SH, IS Lee, HS Kim, MK Choi, DW Hwang, SY Kin and HG Choi. 2012. Distribution of persistent organic pollutants (POPs) in sediment and organism collected from various culturing grounds, Korea. The Sea 17:262-269.
16 Chan WK and KM Chan. 2012. Disruption of the hypothalamic-pituitary-thyroid axis in zebrafish embryo-larvae following waterborne exposure to BDE-47, TBBPA and BPA. Aquat. Toxicol. 108:106-111.
17 Chen D and RC Hale. 2010. A global review of polybrominated diphenyl ether flame retardant contamination in birds. Environ. Int. 36:800-811.
18 Choi H, JW Lee, YH Park, IS Lee, S Heo and UK Hwang. 2018. Ecotoxic evaluations of BDE-47 and BDE-209 using Rotifer (Brachionus plicatilis). Korean J. Environ. Biol. 36:43-49.
19 Danish EPA. 1999. Report No. 494: Brominated flame retardants: substance flow analysis and assessment of alternatives. Danish Environmental Protection Agency.
20 Darnerud PO, GS Eriksen, T Johannesson, PB Larsen and M Viluksela. 2001. Polybrominated diphenyl ethers: occurrence, dietary exposure, and toxicology. Environ. Health Perspect. 109:49-68.
21 Darnerud PO. 2003. Toxic effects of brominated flame retardants in man and in wildlife. Environ. Int. 29:841-853.
22 de Wit CA. 2002. An overview of brominated flame retardants in the environment. Chemosphere 46:583-624.
23 Du HY, L Zhu, Z Chen, Y Li and ZH Duan. 2008. The progress of study on the toxicological effects of deca-brominated diphenyl ether. J. Toxicol. 22:50-52.
24 Feng M, RJ Qu, C Wang, L Wang and Z Wang. 2013. Comparative antioxidant status in freshwater fish Carassius auratus exposed to six current-use brominated flame retardants: A combined experimental and theoretical study. Aquat. Toxicol. 140-141:314-323.
25 Hardy ML. 2002. The toxicology of the three commercial polybrominated diphenyl oxide (ether) flame retardants. Chemosphere 46:757-777.
26 Hardy ML, R Schroeder, J Biesemeier and O Manor. 2002. Prenatal oral (gavage) developmental toxicity study of decabromodiphenyl oxide in rats. Int. J. Toxicol. 21:83-91.
27 Hardy ML, M Banasik and T Stedeford. 2009. Toxicology and human health assessment of decabromodiphenyl ether. Crit. Rev. Toxicol. 39:1-44.
28 Hassanin A, K Breivik, SN Meijer, E Steinnes, GO Thomas and KC Jones. 2004. PBDEs in European background soils: levels and factors controlling their distribution. Environ. Sci. Technol. 38:738-745.
29 Hong SH, UH Yim, WJ Shim, DH Li and JR Oh. 2006. Nationwide monitoring of polychlorinated biphenyls and organochlorine pesticides in sediments from coastal environment of Korea. Chemosphere 64:1479-1488.