Browse > Article

Biochemical and Histopathological Changes of Rockfish, Sebastes schlegeli by Dietary Benzo(a)pyrene  

Park Dae Kuk (부경대학교 수산생명의학과)
Kim Jae Won (부경대학교 수산생명의학과)
Jee Jung-Hoon (부경대학교 수산생명의학과)
Park Soo Il (부경대학교 수산생명의학과)
Kang Ju Chan (부경대학교 수산생명의학과)
Publication Information
Korean Journal of Environmental Biology / v.22, no.3, 2004 , pp. 387-393 More about this Journal
Abstract
Experiments were carried out to investigate the lipid peroxidation (LPO), superoxide dismutase (SOD) activity and histopathological change of hepatic tissue for rockfish, Sebastes schlegeli after feeding sub-chronic dietary Benzo(a)pyrene (BaP) in the concentration of 0 (control), 0.5, 1.0, 1.5, 2.0 mg $kg^{-1}$ dry food of diet for 30 days. In 2.0 mg $kg^{-1}$ dry food group, the significant increase of LPO was observed in all period, and SOD activity was incresed at 30 days significantly in the same concentration. In the histological investigation of liver, there was the swelling of hepatic cells at 10 days over the 1.0 mg $kg^{-1}$ dry food concentration. At 30 days Periodic acid-Schiff (PAS) positive granule was observed in the same group and at 20 days was observed in 2.0 mg $kg^{-1}$ dry food group. And there was necrosis of hepatic cell in some fish of 2.0 mg $kg^{-1}$ dry food group at 30 days.
Keywords
Sebastes schlegeli; benzo(a)pyrene; lipid peroxidation; superoxide dismutase; histophathological change; dietary;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Achuba F. 2002. Superoxide dismutase and lipid peroxidation levels in fish from the ethiope river in Southern Nigeria. Bull. Environ. Contam. Toxicol. 69: 892-899   DOI   PUBMED   ScienceOn
2 Ahmad I, T Hamid, M Fatima. HS Chand, SK Jain, M Athar and S Raisuddin. 2000. Induction of hepatic antioxidants in freshwater catfish (Channa punctatus Bloch) is a biomarker of paper mill effluent exposure. Biochim. Biophys. ACTA 1523:37-48   DOI   ScienceOn
3 Canova S, P Degan, LD Peters, DR Livingstone, R Voltan and P Venier. 1998. Tissue dose, DNA adducts, oxidative DNA damage and CYPlA-immunopositive protein in mussels exposed to waterborne benzo[a]Pyrene. Mut. Res. 399:17-30   DOI
4 Majhi S, BS Jena and BK Patnaik. 2000. Effect of age on lipid peroxides, lipofuscin and ascorbic acid contents (if the lungs of male garden lizard. Comp. Biochem. Physiol. 1260:293-298
5 Plante-Cuny MR, C Salen-Picard, C Grenz, R Plante, E Alliot and C Barranguet. 1993. Experimental field study of the effects of crude oil, drill cuttings and matural biodeposits on microphyte- and macrozoobenthic communities in a Mediterranean area. Mar. Biol. 117:355-366   DOI   ScienceOn
6 Vetter RD, MC Carrey and JS Patton. 1985. Coassimilation of dietary fat and. benzo(a)Pyrene in the small intestine: an absorption model using the killifish. J.Lipid Res. 26:428-434
7 Ozcan E, N Uner and L Tamer. 2002. Comparison of $Na^+$ $Na^+$-ATPase activities and malondialdehyde con-tents in liver tissue for three fish species exposed to azinphosmethyl. Bull. Environ. Contam. Toxicol. 69:271-277   DOI   ScienceOn
8 Van Veld PA, RD Vetter, RF Lee and JS Patton. 1987. Dietary fat inhibits the intestinal metabolism of the carcinogen benzo[a]Pyrene in fish. J. Lipid Res. 28:810-817
9 Shaheen AA, Abd El-Fattah and MZ Gad. 1996. Effect of various stressors on the level of lipid peroxide, antioxidants and $Na^+$ $K^+$ -ATPase activity in rat brain. Experientia 52:336-339   DOI   PUBMED   ScienceOn
10 Junqueira LC, J Carneiro and R Kelley. 1992. Basic hisotology., Korean medical publishing Co. 23-36pp
11 John AB and DA Steven. 1978. Microsome lipid peroxidation. Methods. Enzymol. 52:302-310   DOI
12 Flohe L and F Otting. 1984. Superoxide dismutase assays, Methods Enzymol. 105:93-104   DOI
13 Hinton DE and DJ Lauren. 1990. Integrative histopatho logical approaches to detecting effect of environmental stressors on fishes. Am. Fish. Soc. Symp. 8:51-66
14 Laher JM, MW Rigler, RD Vetter, JA Barrowman and JS Patton. 1984. Similar bioavailability and lymphatic transport ofbenzo[a]pyrene when administered to rats in different amounts of dietary fats. J. Lipid Res. 25:1337-1342
15 Baumard P, H Budzinski and P Garrieues. 1988. PAHs in Arcachon Bay, France : origin and biomonitoring with caged organisms. Mar. Pollut. Bull. 36:577-586
16 Copper RU, LM Clough, MA Farwell and TL West. 2002. Hypoxia-induced metabolic and andtioxidant enzymatic activities in the estuarine fish Leiostomus xanthurus. J. Exper. Mar. Biol. Ecol. 279:1-20   DOI   ScienceOn
17 Tocher DR, G Mourente, AVD Eecken, JO Evjemo, E Diaz and JG Bell, I Geurden. P Lavens and Y Olsen. 2002. Effcts of dietary vitamin E on antioxidant defence mec-hanism of juvenile turbot (Scophthalmus maximus L.), halibut (Hippoelossus hippoglossus L.) and sea bream (Sparus aurata L.). Aqua. Nutr. 8:195-207   DOI   ScienceOn
18 Wright PA, SF Perry and TW Moon. 1989. Regulation of hepatic gluconeogenesis and glycogenolysis by cate-cholamines in rainbow trout during environmental hypoxia. J. Exper. Biol. 146:169-188
19 Sire MF, C Lutton and JM Vernier. 1981. New views on intestinal absorption of lipids in teleostean fishes : An ultrastructural and biochemical study in the rainbow trout. J. Lipid. Res. 22:81-94
20 Van Veld PA, JS Patton and RF Lee. 1988. Effect ofpreex-posure to dietary benzo[a]Pyrene(BP) on the Grstpass metabolism of BP by the intestine of toadfish (Opsanus tau): In vivo studies using portal veincatheterized fish. Toxicol. Appl. Pharmacol. 92:255-265   DOI   ScienceOn
21 Schwaiger J, OH Spieser, C Bauer, H Ferling, U Mallow, W Kalbfus and RD Negele. 2001. Chronic toxicity of nonylphenol and ethinylestradiol : haematological and histopathological effects in juvenile common carp (Cyp-rinus carpio). Aqua. Toxicol. 51:69-78
22 Kim CS, SG Lee, CK Lee, HG Kim and J Jung. 1999. Reactive oxygen species as causative agents in the ichthyotoxicity of the red tide denoflagellate CochI-odinium potykridoides. J. Plank. Res. 21:2105-2115   DOI
23 Zaroogian G, G Gardner and DB Horowitz, R Gutjahr Gobell, R Haebler and L Mills. 2001. Effects of 17)3 estradiol, o, p-DDT, octylphenol and p, P'-DDE on gonadal development and liver and kidney pathology in juvenile male summer flounder (ParaUchthys dentatus). Aquat. Toxicol. 54:101-112   DOI   PUBMED   ScienceOn
24 Stange K and J Klungsoyr. 1997. Organochlorine contaminants in fish and polycyclic aromatic hydrocarbons in sediments from the Barents Sea. ICES. J. Mar. Sci. 54:318-332   DOI   ScienceOn
25 Thophon S, M Kruatrachue, ES Upatham, P Pokethitiyook, S Sahaphong and S Jaritkhuan. 2003. Histopatholo-gical alterations of white seabass, Lates catcarifer, in acute and subchronic cadmium exposure. Environ. Pollut. 121:307-320   DOI   ScienceOn
26 Herbert V, R Zalusky and CS Davidson. 1963. Correlation of folate deficiency with alcoholism and associated macrocytosis anemia and liver disease. Ann. Int. Med. 58:977-988   DOI   ScienceOn