[KSCI] Korea Science Citation Index Service

Pine Needle Oil and Korean Medicinal Herb Complex Protect Hyperlipidemia and Liver Cell Damage Induced by Alcohol

Park, Kap-Joo (Department of Biological Sciences, Konkuk University)
Kim, Kang-Sung (Department of Food Science and Nutrition, Yongin University)
Ahn, Ki-Heung (Department of Biological Sciences, Konkuk University)
Rhee, Joon-Shick (Department of Biological Sciences, Korea Advanced Institute of Science and Technology)

Publication Information

Korean Journal of Environmental Biology / v.21, no.4, 2003 , pp. 410-414 More about this Journal

Abstract

The effect of treatment with pine needle oil complex (complex of pine needle oil and Korean medicinal herbs) upon rat hepatocytes exposed to alcohol was investigated. We compared body weight gain and ratios of liver and kidney to body weight and the serum biochemistry of rats administered both alcohol and Pine needle oil complex to control rats treated with alcohol alone. Pine needle oil complex treatment resulted in a significant reduction in the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and triglycerides (TG) compared to the control rats. These data suggest that Pine needle oil complex represents an excellent candidate for protection of rat hepatocytes from alcohol-mediated damage.

Keywords

Pine needle oil complex; rat liver cell; alcohol;

Citations & Related Records

Reference

1	Ethanol-induced liver fibrosis in rats fed high fat diet / [ Tsukamoto H;SJ Towner;LM Ciofalo;SW French ] / Hepatology
2	/ [ But PPH (et al. eds.) ] / International Collation of Traditional and Folk Medicine.
3	Serum Lipids and risk of coronary artery disease / [ Castelli WP;PW Wilson;D Levy;K Anderson ] / Atheroscl. Rev.
4	/ [ Grieve M. ] / A Modern Herbal
5	Alcoholconsumption, nutrient intake and relative body weight among U.S. adults / [ Gruchow HW;KA Sobocinski;JJ Barboriak;JG Scheller ] / Am. J. Clin. Nutr.
6	/ [ Sherlock S ] / Disease of the liver and Biliary System
7	Impaired lipid and vitamin E absorption related to atrophy of the pancreas in selenium-deficient chicks / [ Thompson JN;ML Scott ] / J. Nutr.
8	/ [ Bode JC;Thurman RG(ed.);T Yontani(ed.);JR Williamson(ed.);B Change(ed.) ] / in Alcohol and Aldehyde Metabolizing System
9	Diphenyleneiodonium sulfate, an NADPH oxidase inhibitor, prevents early alcohol-induced liver injury in the rat / [ Kono H;I Rusyn;T Uesugi;S Yamashina;HD Connor;A Dikalova;RP Mason;RG Thurman ] / Am. J. Physiol. Gastrointest. Liver Physiol
10	Dietary management of hyperlipoproteinmia / [ Levy RI;M Bonnell;ND Ernst ] / J. Am. Diet. Assoc.
11	Insights into the pathogenesis of alcoholic liver necrosis and fibrosis / [ Tsukamoto H;K Gaal;SW French ] / Hepatology
12	Cholesterol and coronary heart disease / [ Rahimtoola SH ] / J. Am Med. Assoc. ScienceOn
13	/ [ Taber CW ] / Taber's Cyclopedic Medical Dictionary, 9th ed
14	/ [ Bown D. ] / Encyclopedia of Herbs and Their Uses
15	Influence of alcohol intake on risk for increased low-density lipoprotein cholesterol in middleaged Japanese man / [ Nakanishi N;H Yoshida;K Nakamura;H Kawashimo;K Tatara ] / Alcohol. Clin. Exp. Res.
16	Pharmacological actions and clinical use of Fructus schizandrae / [ Liu GT ] / Chin. Med. J.(Engl).
17	/ [ Budavari S.(ed.) ] / The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals, 12th ed.
18	Alcoholic liver injury:pathogenesis and therapy in 2001 / [ Lieber CS ] / Pathol. Biol. ScienceOn
19	Influence of chronic ethanol intake on obesity, liver steatosis and hyperlipidaemia in the zucker fa/fa rat / [ Karsentry BC;F Chanussot;M Ulmer;G Debry ] / Br. J. Nutr. ScienceOn
20	The energy cost of the metabolism of drugs, including ethanol / [ Piola RC;CS Lieber ] / Phamacology
21	Effects of chronic ethanol feeding on serum lipoprotein metabolism in the rat / [ Baraona E;CS Lieber ] / J. Clin. Inverst
22	Energy wastage in rats given drugs that induce microsomal enzymes / [ Piola RC;CS Lieber ] / J. Nutr.
23	Selenium and acute alcoholism / [ Cutta SK;Miller Pa;:B Greenberg;OA Levander ] / Am. J. Clin. Nutr.
24	Effects of alcohol ingestion on lipids and lipoproteins in normal men:isocaloric metabolic studies / [ Glueck CJ;E Hogg;C Allen;PS Gartside ] / Am. J. Clin. Nutr.
25	Ebselen prevents early alcohol-induced liver injury in rats / [ Kono H;GE Arteel;I Rusyn;H Sies;RG Thurman ] / Free Radic. Biol. Med. ScienceOn
26	/ [ Nadkarni KM ] / Indian Materia Medica