Browse > Article
http://dx.doi.org/10.7847/jfp.2018.31.1.001

Molecular epidemiology and virulence changes of infectious hematopoietic necrosis virus (IHNV) in East Asia  

Nishizawa, Toyohiko (Department of Aqualife Medicine, Chonnam National University)
Publication Information
Journal of fish pathology / v.31, no.1, 2018 , pp. 1-8 More about this Journal
Abstract
Causative agent of infectious hematopoietic necrosis (IHN) belonging to genus Novirhabdovirus (Rhabdoviridae). Economic losses caused by IHNV are serious in mainly Oncorhynchus spp. including rainbow trout O. mykiss and Atrantic salmon Salmo salar. IHNV was initially found by endemic presence in U.S. West Coast for sockeye salmon fry O. nerka and chinook salmon fry O. tshawytscha in the 1950s, and it has spread to Japan, Korea and Taiwan in the 1970s, and also to Italy and France in the 1990s. Currently, IHNV is detectable in many parts of the world, including Russia and South America. Mortality due to IHNV infection in fish with ${\leq}0.5g$ of body weight reaches 60% to 100%, while the mortality reduces by fish growing. In recent years, onset of IHNV infection has increased also in fish with large sizes. Here, we introduce molecular epidemiology and virulence changes of IHNV in East Asia, furthermore, we discuss on future prospects in IHNV researches.
Keywords
IHNV; molecular epidemiology; virulence change; detection; identification; research prospect;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 Yoshimizu, M., Nomura, T., Ezura, Y. and Kimura, T. Surveillance and control of infectious hematopoietic necrosis virus (IHNV) and Oncorhynchus masou virus (OMV) of wild salmonid fish returning to the northern part of Japan 1976-1991. Fish. Res., 17, 163-173, 1993.   DOI
2 Yoshimizu, M., Sami, M. and Kimura, T. Survivability of infectious hematopoietic necrosis virus in fertilized eggs of masu and chum salmon. J. Aquat. Anim. Health, 1, 13-20, 1989.   DOI
3 Winton JR. Immunization with viral antigens: infectious haematopoietic necrosis. In: Gudding R, Lillehaug A, Midtlyng PJ, Brown F (eds) Fish vaccinology, Vol. 90. Developments in biological standardization. Karger, Basel, pp. 211-220, 1997.
4 Wolf, K.Infectious hematopoietic necrosis. In Wolf, K. (ed) Fish viruses and fish viral diseases. Cornell University Press, Ithaca, N.Y., pp. 83-114, 1988.
5 Alonso, M. and Leong, J.C. Licensed DNA vaccines against infectious hematopoietic necrosis virus (IHNV). Recent Pat DNA Gene Seq., 7, 62-65, 2013.   DOI
6 Kim, H.J., Ohseko, N., Nishizawa, T. and Yoshimizu, M.. Protection of rainbow trout from infectious hematopoietic necrosis (IHN) by injection of infectious pancreatic necrosis virus (IPNV) or Poly(I:C). Dis. Aquat. Org., 83, 105-113. 2009.   DOI
7 Dietzgen, R.G., Calisher, C.H., Kurath, G., Kuzmin, I.V., Rodriguez, L.L., Stone, D.M., Tesh, R.B., Tordo, N., Walker, P.J., Wetzel, T. and Whitfield, A.E., Family Rhabdoviridae, In: King, A.M.Q., Adams, M.J., Carstens, E.B., Lefkowitz, E.J. (eds) Virus Taxonomy: Ninth report of the international committee on taxonomy of viruses. Elsevier Academic Press, San Diego, CA, pp. 686-713. 2012.
8 Engelking, H.M. and Leong, J.C. The glycoprotein of infectious hematopoietic necrosis virus elicits neutralizing antibody and protective responses, Virus Res., 13, 213-230, 1989.   DOI
9 Hatori, S., Motonishi, A., Nisizawa, T. and Yoshimizu M.. Virucidal effect of disinfectants for Onchorhyncus masou virus (OMV). Fish Pathol., 38, 185-187, 2003.(Japanese with English abstract)   DOI
10 Kim, H.J., Cho, J.K., Hwang, H.K., Oh, M.J. and Nishizawa, T. Establishment and characterization of the epithelioma papulosum cyprini (EPC) cell line persistently infected with infectious pancreatic necrosis virus (IPNV), an aquabirnavirus. J. Microbiol., 50, 821-826, 2012.   DOI
11 Kim, W.S., Oh, M.J., Nishizawa, T., Park, J.W., Kurath, G. and Yoshimizu, M. Genotyping of Korean isolates of infectious hematopoietic necrosis virus (IHNV) based on the glycoprotein gene. Arch. Virol., 152, 2119-2124, 2007.   DOI
12 Kimura, T. and Yoshimizu, M. Viral diseases of fish in Japan, Ann. Rev. Fish Dis., 1, 67-82, 1991.   DOI
13 Bootland, L.M. and Leong, J.C. Infectious hematopoietic necrosis virus, In Woo, P.T.K. and Bruno, D.W. (eds) Viral, Bacterial and Fungal Infections. Vol. 3, 2nd Edition. CAB international, pp.66-109, 2011.
14 Mulcahy, D. and Pascho, R.J. Adsorption to fish sperm of vertically transmitted fish viruses. Science, 225, 333-335, 1984.   DOI
15 Kurath, G., Garver, K.A., Troyer, R.M., Emmenegger, E.J., Einer-Jensen, K. and Andersen, E.D. Phylogeography of infectious haematopoietic necrosis virus in North America. J. Gen. Virol., 84, 803-814, 2003.   DOI
16 Lorenzen, N., Lorenzen, E., Einer-Jensen, K. and LaPatra, S.E. Immunity induced shortly after DNA vaccination of rainbow trout against rhabdoviruses protects against heterologous virus but not against bacterial pathogens. Dev. Comp. Immunol., 26, 173-179, 2002.   DOI
17 Mochizuki, M., Kim, H.J., Kasai, H., Nishizawa, T. and Yoshimizu, M. Virulence change of infectious hematopoietic necrosis virus against rainbow trout Oncorhynchus mykiss with viral molecular evolution. Fish Pathol., 44, 159-165, 2009.   DOI
18 Nishizawa, T., Iida, H.,Takano, R., Isshiki, T., Nakajima, H. and Muroga, K. Genetic relatedness among Japanese, American and European isolates of viral hemorrhagic septicemia virus (VHSV) based on partial G and P genes. Dis. Aquat. Org., 48, 143-148, 2002.   DOI
19 Nishizawa, T., Kinoshita, S., Higashi, S., Kim, W.S. and Yoshimizu, M. Nucleotide diversity of Japanese isolates of infectious hematopoietic necrosis virus (IHNV) based on the glycoprotein gene. Dis. Aquat. Org., 71, 267-272, 2006.   DOI
20 Nishizawa, T., Takami, I., Kokawwa, Y. and Yoshimizu, M. Fish immunization using a synthetic double-stranded RNA Poly(I:C), an interferon inducer, offers protection against RGNNV, a fish nodavirus. Dis. Aquat. Org., 83, 115-122, 2009.   DOI
21 Nishizawa, T., Takami, I., Yang, M. and Oh, M.J. Live vaccine of viral hemorrhagic septicemia virus (VHSV) for Japanese flounder at fish rearing temperature of $21^{\circ}C$ instead of Poly(I:C) administration. Vaccine, 29, 8397-8404, 2011.   DOI
22 Sohn, S.-G., Park, M.-A., and Park, J.-W. Studies on viral disease of masu salmon, Oncorhynchus masou- II. Isolation of infectious hematopoietic necrosis virus from masu salmon fry. J. Fish Pathol., 6, 87-92, 1993.
23 Nishizawa, T., Gye, H.J., Takamia, I. and Oh, M.J. Potentiality of a live vaccine with nervous necrosis virus (NNV) for sevenband grouper Epinephelus septemfasciatus at a low rearing temperature. Vaccine, 30, 1056-1063, 2012.   DOI
24 O.I.E. (world organization for animal health) Infectious hematopoietic necrosis. Chapter 2.3.4, Manual of diagnostic tests for aquatic animals. http://www.oie.int/international-standard-setting/aquatic-manual/access-online/, 2016.
25 Oh, S.-Y., Oh, M.-J. and Nishizawa, T. Potentiality of a live vaccine with red seabream iridovirus (RSIV) for rock bream Oplegnathus fasciatus by controlling fish rearing temperature. Vaccine, 32, 363-368, 2014.   DOI
26 Takami, I., Kwon S.R., Nishizawa, T. and Yoshimizu, M. Protection of Japanese flounder Paralichthys olivaceus from viral hemorrhagic septicemia (VHS) by Poly(I:C)-immunization. Dis. Aquat. Org., 89, 109-115, 2010.   DOI
27 Yoshimizu M. Disease problems of salmonid fish in Japan caused by international trade. Rev. Sci. Tech. Off. Int. Epiz., 15, 533-549, 1996.   DOI
28 Yoshimizu, M. Control strategy for viral diseases of salmonids and flounder, In: Lee, C.S., O'Bryen, P.J. (eds) Biosecurity in aquaculture production systems: Exclusion of pathogens and other undesirables., World Aquaculture Society, proceedings of AIP workshop, Baton Rouge, Louisiana, USA, pp. 35-41, 2003.
29 Yoshizumu, M. and Kasai, H.. Sterilization of fish rearing water and wastewater at seedling production facilities. Industrial Water, 523, 13-26, 2002. (Japanese)