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Changes of hematological parameters in olive flounder Paralichthys olivaceus exposed to pentachlorophenol  

Kang, Ju-Chan (Dept. of Aquatic Life Medicine, Pukyong National University)
Min, Eun-Yong (Dept. of Aquatic Life Medicine, Pukyong National University)
Publication Information
Journal of fish pathology / v.23, no.2, 2010 , pp. 189-198 More about this Journal
Abstract
Experiments were carried out to determine the hematological changes in olive flounder, Paralichthys olivaceus, after sub-chronic dietary pentachlorophenol (PCP) concentrations (0, 0.1, 0.5 and 1.0 mg/kg) exposure 6 weeks. The RBC count, Ht and Hb were significantly decreased in PCP 0.5 mg/kg exposed flounder compared to control group. The flounder exposed to PCP concentration 0.5 mg/kg started to increase significantly in serum magnesium concentrations after 4 weeks. The low concentration of serum calcium concentration was observed at 6 weeks of the experiment in PCP concentration 0.5 mg/kg. Although serum total protein concentrations was significantly reduced compared to the control group at PCP concentration 0.5 mg/kg, serum glucose concentration was found to be significantly increased over the control group. A significant increment of GOT, GPT and LDH activities in the flounder serum was noticed after 4 weeks at PCP concentrations over 0.5 mg/kg without typical changes of Al-P. These results indicate that flounder can be affected by PCP in terms of inorganic matter, organic matter and enzyme activity in serum when they were exposed to the PCP concentrations 0.5 mg/kg or higher.
Keywords
Paralichthys olivaceus; Pentachlorophenol (PCP); Serum; Hemochemical changes;
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