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Stability and efficacy of formalin-killed Streptococcus iniae vaccine for olive flounder, Paralichthys olivaceus  

Cho, Mi-Young (국립수산과학원)
Lee, Deok-Chan (국립수산과학원)
Kim, Jin-Woo (국립수산과학원)
Do, Jung-Wan (국립수산과학원)
Lee, Joo-Seok (내수면양식연구소)
Kim, Myoung-Sug (국립수산과학원)
Choi, Mi-Young (부경대학교)
Kim, Yi-Cheong (어류연구센터)
Kang, Bo-Kyou (녹십자수의약품주식회사)
Yoon, Yong-Dhuk (녹십자수의약품주식회사)
Publication Information
Journal of fish pathology / v.19, no.2, 2006 , pp. 165-172 More about this Journal
Abstract
This study was performed to verify the stability and efficacy of Streptococcus iniae formalin killed cells on storage at refrigerator temperature in olive flounder, Paralichthys olivaceus. The vaccines preserved for 6, 12 and 15months showed high stability of potency. The antibody titers and protection efficacy to challenge test were significantly higher in booster immunized groups than prime immunized groups during storage. Especially, above 60% of relative percent survival obtained at low antibody revel in prime immunized groups indicates that innate and non-specific immune system might act against the S. iniae challenged.
Keywords
Streptococcus iniae; flounder; Paralichthys olivaceus; formalin-killed vaccine; stability; efficacy;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
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