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http://dx.doi.org/10.12925/jkocs.2022.39.4.580

A Study on the Antioxidant, Whitening and Anti-Inflammatory Activities of Trichosanthis Cucumeroidis Radix Extract  

You, Seon-Hee (Department of Beauty Stylist Major in Skin Care, Yeonsung University)
Lee, Eun-Ju (Department of Beauty Stylist Major in Skin Care, Yeonsung University)
Publication Information
Journal of the Korean Applied Science and Technology / v.39, no.4, 2022 , pp. 580-587 More about this Journal
Abstract
In this study, the physiological activity effect of trichosanthis cucumeroidis radix extract on antioxidant activity, whitening, and anti-inflammatory activity was checked, and the possibility of its use as a functional material was checked. The purpose of this study was to confirm the antioxidant activity through DPPH radical scavenging activity of trichosanthis cucumeroidis radix extract, whitening activity effect through melanin production inhibition ability for melanin cell B16F10 melanoma cell, and anti-inflammatory activity effect through NO production inhibition ability for macrophage RAW 264.7 cell. As a result of the study, the concentration-dependent DPPH radical scavenging activity of the trichosanthis cucumeroidis radix extract was confirmed, and DPPH radical scavenging activity similar to that of the positive control Ascorbic acid was confirmed. It was confirmed that the melanin production inhibitory activity induced by 100 nM 𝛼-MSH and the NO production inhibitory ability induced by LPS 1 ㎍/mL were significantly suppressed. Accordingly, it is considered that the trichosanthis cucumeroidis radix extract may be used as a functional material having antioxidant, whitening, and anti-inflammatory effects.
Keywords
Whitening activity; trichosanthis cucumeroidis radix extract; antioxidant activity; anti-inflammatory activity; functional materials;
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Times Cited By KSCI : 6  (Citation Analysis)
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