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http://dx.doi.org/10.12925/jkocs.2022.39.3.462

Evaluation on the Whitening Effect of Nypa fruticans wurmb Extracts  

Kim, Il-Chool (Dept. of Bio-Cosmetic Science Joongbu University)
Publication Information
Journal of the Korean Applied Science and Technology / v.39, no.3, 2022 , pp. 462-470 More about this Journal
Abstract
The purpose of this study was to investigate the role of the Nypa fruticans extracts as a cosmetic additive. The tyrosinase inhibitory effects showed 52.0% at 1,000 ㎍/mL concentration. A cell viability test, measured on melanoma cell (B16F10) hot water extract of nypa fruticans showed 84.8% at 100 ㎍/mL concentration. The protein expression inhibitory effects of nypa fruticans extracts were measured by western blot at 25, 50, 100 ㎍/mL concentration and the β-actin. Results showed that the expression inhibition rates of the MITF, TRP-1, TRP-2, tyrosinase protein were decreased by 70.7%, 83.3%, 45.7%, 45.9% at 100 ㎍/mL concentration, respectively. It was concluded that nypa fruticans extracts had the whitening effects and thus could be applied for cosmetics as a natural ingredient.
Keywords
Nypa fruticans; Natural ingredient; Tyrosinase; Cell viability; Whitening;
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Times Cited By KSCI : 3  (Citation Analysis)
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