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http://dx.doi.org/10.12925/jkocs.2022.39.1.27

Evaluation of Antiaging Activity on Lycium chinense Miller. Extracts  

Lee, Yong-Hwa (Department of Cosmetic biotechnology, Institute of Basic Sciences, Hoseo University)
Kim, ․Na-Yeon (Department of Cosmetic science, Hoseo University)
Jo, Il-young (Department of Cosmetic science, Hoseo University)
Yi, Yong-Sub (Department of Cosmetic biotechnology, Institute of Basic Sciences, Hoseo University)
Publication Information
Journal of the Korean Applied Science and Technology / v.39, no.1, 2022 , pp. 27-33 More about this Journal
Abstract
The purpose of this study was to investigate the functionality of Lycium chinense Miller. as a functional cosmetic material. The total polyphenol content in the extract was 17.3 mg/mL, and as a result of confirming cytotoxicity through MTT assay before the enzyme experiment, it was confirmed that it did not affect cell growth at all concentrations below 1000 ㎍/mL. As a result of conducting DPPH radical scavenging tests as an antioxidant efficacy test, it showed 84.97% scavenging ability at a concentration of 1000 ㎍/mL, and showed very excellent antioxidant efficacy in SOD-like activity test with a result of 80.54% at 1000 ㎍/mL. The measured elastase inhibitory activity, the inhibition rate of 50.93% was observed at 1000 ㎍/mL, indicating that the extract of Lycium chinense Miller. was effective in inhibiting elastase. All these findings suggested that 70% ethanol extract of Lycium chinense Miller. was confirmed as a functional cosmetic material by confirming its antioxidant and anti-wrinkle efficacy.
Keywords
Anti-oxidantion; anti-wrinkle; functional cosmetics; natural materials; Lycium chinense Miller;
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