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http://dx.doi.org/10.12925/jkocs.2021.38.6.1370

A study on antioxidant and anti-inflammatory effects of domestic blended essential oils  

Jung, Sook Heui (Department of Cosmetology Science, Nambu University)
Lee, Eun Kyung (Nambu University Industry-Academic Cooperation Foundation, Healing Aroma Commercialization Project Group)
Publication Information
Journal of the Korean Applied Science and Technology / v.38, no.6, 2021 , pp. 1370-1382 More about this Journal
Abstract
Previous studies have been conducted on domestic materials as a single extract. Research on complex mixtures for maximizing plant characteristics by individual extraction and potential interference with effects is insufficient. Therefore, this study confirmed the GC-MSD according to the extraction of essential oils for Agastache rugosa O. Kuntze(AR), Pinus densiflora Sieb. et Zuccarini(PD), Curcuma longa, Curcuma domestica(CC), Zingiber officinale Roscoe(ZR), Foeniculum vulgare Miller(FV), and Citrus medica L. var. sarcodactylis Swingle(CS). The cytotoxicity, antioxidant, and anti-inflammatory properties of the blending oil were confirmed to confirm its potential as a cosmetic material. As a result of analyzing GC-MSD aroma components, the main components were estragole of AR, à-Pinene for PD, Zingiberene for CC and ZR, Anethole from FV, and D-Limonene for CS. At a concentration of 100 uL/mL with no confirmed cytotoxicity, NO production was inhibited by 70.62%, DPPH radical scavenging activity was 64.03%, and ABTS radical scavenging activity was 89.55%. Through this, blended essential oil suggests the possibility of useful application as a raw material with antioxidant and anti-inflammatory effects in the cosmetic and food industries.
Keywords
Blending oil; Aroma ingredient; Antioxidant; Anti-inflammatory; Pharmaceutical industry;
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1 Y. R. kwan, K. S. Youn. "Antioxidant and physiological activities of Hijikia fusiforme by extraction methods". Korean Journal of Food Preservation. Vol.24, No.5, pp. 631-637, (2017).   DOI
2 S. K. Kim. "Antioxidant and anti-inflammatory activities of extracts from Ledum palustre L.". Korean Journal of Food Preservation. Vol. 24, No. 7, pp. 1025-1033, (2017).   DOI
3 H. J. Park, J. S. Lee, J. D. Lee, N. J. Kim, J. H. Pyo, J. M. Kang, I. H. Choe, S. Y. Kim, B. S. Shim, J. H. Lee, S. B. N. Lim, "The Anti-inflammatory Effect of Cinnamomi Ramulus", Journal of Korean Oriental Medicine, Vol. 26, No. 2, pp. 140-151, (2005).
4 Katsuyama. K, M. Shichiri, F. Marumo, Y. Hirata. "NO Inhibits Cytokine-Induced iNOS Expression and NF-κB Activation by Interfering With Phosphorylation and Degradation of IκB-α". Arteriosclerosis, Thrombosis, and Vascular Biology. Vol. 18, No. 11, pp. 1796-1802, (1998).   DOI
5 J. H. Choi, J. H. Park, Y. J. Cho. "Development of Functional Products Using Chamaecyparis Obtusa Heartwood Essential Oil". Journal of Convergence for Information Technology. Vol. 11, No. 2, pp. 211-218, (2021).   DOI
6 S. H. Shin, H. K. Kim, H. J. Chi. "Production of Giant Hyssop Oil by Plant Tissue Culture". Korean Journal of Pharmacognosy. Vol. 22, No. 2, pp. 91-94, (1991).
7 J. S. Kim, M. S. Koh, Y. H. Kim, M. G. Kim, J. S. Hong. "Volatile Flavor Components of Korean Ginger(Zingiber officinale Roscoe)". Korean Journal of Food Science and Technology. Vol. 23, No. 2, pp. 141-149, (1991).
8 J. C. Park, Tropical Fruits as Medicine, pp. 192-197, Blue Happiness,
9 H. H. Jeong. "A Study on Physicochemical Properties and Biological Activities of Citrus medica leaf Tea Prepared by Different Drying Methods", doctor's thesis of Sunchon National University. (2014).
10 H. Y. Ji, M. G. Park, S. Y. Joo. "Antioxidant effect of complex extracts from pine needle, green tea, and sea buckthorn leaves". Korean Journal of Food Science and Technology. Vol. 53, No. 3, pp. 290-295, (2021).   DOI
11 S.G. Park, E. J. Park, S. G. Lee, W. S. Song. "Citrus medica Antibacterial and antioxidant activity of citron extract". Korean Society of Food and Nutrition Science Conference Presentation. Vol. 2013, No. 11, pp. 286-286, (2013).
12 J. S. Park, S. H. Jung. "Effects of Sandalwood Essential Oil on the iNOS Expression and Proinflammatory Cytokine Production". Yakhak Hoeji. Vol. 57, No. 1, pp. 70-75, (2013).
13 M. S. Blois. "Antioxidant determination by the use of a stable free radical". Nature. Vol. 181, pp. 1199-1200, 1958.   DOI
14 D. J. Charles, J. E. Simon, M. P. Widrlechner. "Characterization of the essential oil of Agastache species". J Agric. Food Chem. Vol. 39, pp. 1945-1949, (1991).
15 J. Baik. "Analysis, Antibacterial, and Insecticide Effects on Domestic Native Fragrant Plants Elsholtzia ciliata and Agastache rugosa". J. Korean Soc. People Plants Environ. Vol. 19, No. 2, pp. 79-83, (2016).   DOI
16 J. S. Choi, B. M. Song, H. J. Park, "Gas Chromatographic Analysis and Cholinesterase Activity of the Essential Oil from Korean Agastache rugosa", Korea Journal of Pharmacognosy, Vol. 47, No. 2, pp. 192-196, (2016).
17 K. S. Kim. "Changes in Growth Characteristics and Curcuminoid Contents of Turmeric Cultivated Using Mother and Finger Seed Rhizomes of Different Sizes". Korean journal of medicinal crop science. Vol. 26, No. 5, pp.354-361, (2018).   DOI
18 S. H. Kang, M. K. Kim, D. G. Seo, G. H. Kim. "Fumigant Toxicity of Essential Oils against Adults of Culex pipiens pallens". The Korean Journal of Pesticide Science. Vol. 10, No. 2, pp. 117-123, (2006).
19 A. Y. Lee, H. S. Kim, G. Y. Choi, J. M. Chun, B. C. Moon, H. K. Kim. "Comparison of Major Compounds in Illicii Veri Fructus by Extraction Solvents". The Korea Journal of Herbology. Vol. 28, No. 6, pp. 47-51, (2013).   DOI
20 E. H. Oh, H. S. Im, C. H. Yoon. "A study on the antibiotic effect using the d-limonene oil extracted to wasted mandarin peels in Cheju". Journal of the Korean Applied Science and Technology. Vol. 26, No. 3, pp. 350-356, (2009).
21 N. Y. Kim, D. S. Park, H. Y. Lee. "Effect of Anti-Skin Wrinkle and Antioxidant of Agastache rugosa Kentz through Fermentation Process of the lactic acid", The Korean Society of Medicinal Crop Science. Vol. 23, No. 1, pp. 37-42, (2015).   DOI
22 D. Y. Im, K. I. Lee. "Antioxidative Activity and Tyrosinase Inhibitory Activity of the Extract and Fractions from Arctium lappa Roots and Analysis of Phenolic Compounds". Korean Journal of Pharmacognosy. Vol. 45, No. 2, pp. 141-146, (2014).
23 M. R. Lee, H. J. Bu. "Antioxidant, Antimicrobial and Melanogenesis Inhibition Effects of 35 species Essential Oil". Jounal of The Korean Society of cosmetology. Vol. 23, No. 4, pp. 677-687, (2017).
24 Awika. J. M, Rooney. L. W, Wu. X, Prio. R. L, Cisneros-Zevallos. L. "Screening methods to measure antioxidant activity of sorghum(Sorghum bicolor) and sorghum products". Journal of Agricultural and Food Chemistry. Vol. 51, No. 23, pp. 6657-6662, (2003).   DOI
25 J. S. Park. "Cytokine Production Inhibitory Effects of Lavender Essential Oil in RAW 264.7 Cells". Nambu University Papers. Vol. 11, pp. 55-60, (2011).
26 C. R. Kim. "Enhancement of Liver Function by Curcuma Extract on Acute Hepatotoxicity in Rat". Korean Society for Food Science of Animal Resources. Vol. 26, No. 3, pp. 386-393, (2006).
27 J. C. Lee, Y. H. Choi, Y.H. Kim. "Essential Oils in Aerial Parts of Agastache rugosa O. Kuntze". Korean Journal of Medicinal Crop Science. Vol.2 No. 2, pp. 168-173, (1994).
28 B. C. Cha. "Changes in the Constituents and Antioxidant Activity in Accordance with the Processing Conditions of Citrus unshiu Markovich". Korean Journal of Pharmacognosy. Vol. 46, No. 1, pp. 23-30, (2015).
29 Dunn C , Sleep J , Collett D. "Sensing an improvement: an experimental study to evaluate the use of aromatherapy, massage and periods of rest in an intensive care unit". Journal of Advanced Nursing. Vol. 21, No. 1, pp. 34-40, (1995).   DOI
30 M. C. Shin, S. H. Jung. "Analysis of Aroma Components by Part of Allium Hookeri and Research on Antioxidant and Anti-inflammatory". Journal of the Korean Applied Science and Technology. Vol. 38, No. 1, pp. 263-270, (2021).   DOI
31 D. S. Han, Y. C. Kim, S. E. Kim, H. S. Ju, S. J. Byun. "Studies on the diterpene constituent of the root of Agastache rugosa O. Kuntze". Korean Journal of Pharmacognosy. Vol. 18, No. 2, pp. 99-102, (1987).
32 W. K. Im, Natural botany, pp. 59-63, Dosu publishers, (1996).
33 Y. J. Surh. "Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances". Mutation Research. Vol. 428, No. 1-2, pp. 305-327, (1999).   DOI
34 B. S. Lee, M. S. Ko, H. J. Kim, I. S. Kwak, D. H. Kim, B. W. Chung. "Separation of 6-Gingerol from Ginger [Zingiber officinale Roscoe] and Antioxidative Activity". Korean journal of biotechnology and bioengineering. Vol. 21, No. 6, pp. 484-488, (2006).
35 H. J. Kim, J. W. Lee, Y. D. Kim. "Antimicrobial Activity and Antioxidant Effect of Curcuma longa, Curcuma aromatica and Curcuma zedoaria". Korean Journal of Food Preservation. Vol. 18, No. 2, pp .219-225, (2011).   DOI
36 J. R. Park, S. H. Park, J. U. Kim, S. W. Kim, S. Y. Lee. "The Effect of Estragole Identified and Extracts from Agastache rugosa O. Kuntze on the Fungal Growth and Metabolism". Journal of Food Hygiene and Safety. Vol. 12, No. 1, pp. 63-70, (1997).
37 Y. M. Seo. "Recovery Effect of Blending Oil on Skin Barrier Damaged by Atopic Dermatitis". Journal of East-West nursing research. Vol. 20, No. 1, pp. 57-62, (2014).
38 Rapper S, Kamatou G, Viljoen A, van Vuuren S. "The in vitro antimicrobial activity of lavandula angustifolia essential oil in combination with other aroma-therapeutic oils". Evid Based Complement Alternat Med. Vol. 2013, pp. 10, (2013).
39 M. J. Hong, J. H. Kim , H. Y. Kim, M. J. Kim, S. M. Kim. "Chemical compositionand biological activity of essential oil of Agastache rugosa (Fisch. & C. A. Mey.) O. Kuntze". Korean Journal of Medicinal Crop Science. Vol. 28, No. 2, pp. 95-110, (2020).   DOI
40 J. K. Jang, Brush leaf medical therapy of miracle, Academi book, (1997).
41 K. C. Sung. "A Study on the Pharmaceutical Characteristics and Analysis of Natural Ginger Extract". Journal of the Korean Applied Science and Technology. Vol. 27, No. 3, pp. 266-272, (2010).
42 Josiane Padilha de Paula, Maria Regina Gomes-Carneiro, Francisco J.R Paumgartten. "Chemical composition, toxicity and mosquito repellency of Ocimum selloi oil". Journal of Ethnopharmacology. Vol. 88, No. 2-3, pp. 253-260, (2003).   DOI
43 A. Murakami, M. Nakashima, T. Koshiba, T. Maoka, H. Nishino, M. Yano, T. Sumida, O. K. Kim, K. Koshimizu, H. Ohigashi. "Modifying effects of carotenoids on superoxide and nitric oxidegeneration from stimulated leukocytes". Cancer Letter. Vol. 149, No. 1-2, pp. 115-123, (2000).   DOI
44 J. Y. Baek, K. S. Kang, A. Y. Lee, H. Y. Kim. "Anti-inflammatory Property of Chicken Feet, Acanthopanax, and Eucommia ulmoides Oliver Mixture Extract in LPS-stimulated RAW 264.7 Macrophage Cells". Korean Society for Biotechnology and Bioengineering Journal. Vol. 35, No. 4, pp. 330-336, (2020).
45 Desai, A., Vyas, T. and Amiji, M. :Cyroroxicity and apoptosis enhancement in brain tumor cells upon coadministration of paclitaxel and ceramide in nanoemulsion formulations. J. Pharm. Sci. 97, 2745 (2008).   DOI