Browse > Article
http://dx.doi.org/10.12925/jkocs.2021.38.5.1265

Bioactive Characteristics of the Astragalus Membranaceus Ethanol & Bioconversion Extracts as functional Cosmetic materials  

Bae, Hye-Kyung (Department of Beauty Care, Bucheon University)
Publication Information
Journal of the Korean Applied Science and Technology / v.38, no.5, 2021 , pp. 1265-1272 More about this Journal
Abstract
This study was intended to investigate the potential of Astragalus membranaceus ethanol extract(AM) and Astragalus membranaceus bioconversion extract(AMB) as functional cosmetic materials. To confirm the antioxidant effect, polyphenol and flavonoid contents were measured, and a study was conducted on skin cell toxicity and skin cell aging through cell experiments. As a result of the antioxidant experiment, the content of polyphenols and flavonoids increased in a concentration-dependent manner in the effects of polyphenols and flavonoids, and it was confirmed that the ethanol extracts were higher than the bioconversion extracts. It was confirmed that the AM and AMB increased the MMP1 expression inhibitory effect in a concentration-dependent manner in HDF cells. Therefore, this study is considered to be very useful as a functional cosmetic material in terms of antioxidant and skin aging prevention when using AM and AMB as functional cosmetic materials.
Keywords
Anti-oxident effects; Anti-aging effects; MMP1; Astragalus membranaceus; Bioconversion;
Citations & Related Records
연도 인용수 순위
  • Reference
1 S. Y. Lee, Y. J. Shin, J. H. Park, S. M. Kim, C. S. Park, "An analysis of the gyungokgo's ingredients and a comparison study on anti-oxidation effects according to the kinds of extract", Korean Journal of Herbology, Vol. 23, No. 2, pp. 123-136, (2008).
2 K. R. Im, M. J. Kim, T. K. Jung, K. S. Yoon, "Analysis of isoflavonoid contents in Astragalus membranaceus Bunge cultivated in different areas and at various ages", Journal of The Korean Society for Biotechnology and Bioengineering, Vol. 25, No. 3, pp. 271-276, (2010).
3 X. Q. Ma, Q. Shi, J. A. Duan, T. T. Dong, K. W. Tsim, "Chemical analysis of Radix Astragali (Huangqi) in China: a comparison with its adulterants and seasonal variations", Journal of Agricultural and Food Chemistry, Vol. 50, No. 1, pp. 4861-4866, (2002).   DOI
4 J. H. Lim, D. C. Jin, J. S. Sung, K. H. Bang, O. T. Kim, S. W. Cha, H. W. Park, "Discrimination of Astragalus membranaceus (Fisch) Bunge from A. membranaceus (Fisch) Bunge var. mongholicus (Bunge) with SCAR marker", Korean Journal of Medicinal Crop Sci, Vol. 15, No. 1, pp. 51-55, (2007).
5 S. H. Min, O. J. Park, "Quality characteristics of Yanggaeng prepared with different amounts of Astragalus membranaceus powder", Journal of East Asian Soc Dietary Life, Vol. 18, No. 1, pp. 9-13, (2008).
6 J. C. Mou, S. N. Lee, M. G. Kim, M. H. Kim, H. J. Kim, H. J. Cho, K. H. Leem, "Effects of Astragali radix extracts on the elastase activity and DPPH and NO scavenging activities", Korea Journal of Herbology, Vol. 26, No. 1, pp. 59-61, (2011).   DOI
7 D. J. McKenna, K. Hughes, K. Jones, Astragalus membranaceus, International Journal of Integrated Medicine, Vol. 4, No. 1, pp. 40-46, (2002).
8 X. G. Du, Y. J. Bai, H. Liang, Z. Y. Wang, Y. Y. Zhao, Q. Y. Zhang, L. Q. Huang, "Solvent effect in 1H NMR spectra of 3. 0. -hydroxy-4", Magnetic Resonance in Chemistry, Vol. 44, No. 1, pp. 708-712, (2006).   DOI
9 Y. D. Zhang, Y. L. Wang, J. P. Shen, D. X. Li, "Hypotensive and anti-inflammatory effects of. Astragalus saponin1, Acta Pharmacologica Sinica", Vol. 19, No. 1, pp. 333-334, (1984).
10 J. S. Lee, Studies on the saponin compounds of astragalus membranaceu", Unpublished Master's thesis, Seoul University, (1997).
11 W. Kalt, A. Hanneken, P. Milbury, F. Tremblay, "Recent research on polyphenolics in vision and eye health", Journal of Agric Food Chem, Vol. 58, No. 7, pp. 4001-4007, (2010).   DOI
12 H. S. Jung, Chemical constituents from the roots of Astragalus membranaceus, Unpublished Master's thesis, Seoul University, (2008).
13 S. A. Kang, M. S. Oh, D. R. Kim, J. U. Kang, W. N. Kim, E. H. Park, M. S. Chang, S. K. Park, "Compositions of Astragali Radix and Angelicae Radix by DPPH radical scavenging activity", The Korea Journal of Herbology, Vol. 21, No. 1, pp. 17-24, (2006).
14 T. K.. Jung, M. J. Kim, K. R. Lim, K. S. Yoon, "Moisturizing and antioxidation effect of Astragalus membranaceus root extract", Journal of the Society of Cosmetic Scientists of Korea, Vol. 32, No. 1, pp. 193-200, (2006).
15 M. J. Kim, K. R. Lim, T. K. Jung, K. S. Yoon, "Anti-aging effect of Astragalus membranaceus root extract", Journal of the Society of Cosmetic Scientists of Korea, Vol. 33, No. 1, pp. 33-40, (2007).
16 M. H. Kang, C. S. Cho, Z. S. Kim, H. K. Chung, K. S. Min, C. G. Park, H. W. Park, "Antioxidative activities of ethanol extract prepared from leaves, seed, branch and aerial part of Crotalaria sessiflora L", Korean Journal of Food Sci Technol, Vol. 34, No. 6, pp. 1098-1102, (2002).
17 B. Halliwell, R. Aeschbach, J. Loliger, O. I. Aruoma, "The characterization of antioxidants, Food Chem Toxicol", Vol. 33, No. 7, pp. 601-617, (1995).   DOI
18 S. Kang, J. H. Chung, J. H. Lee, G. J. Fisher, Y. S. Wan, E. A. Duell, J. J. Voorhees, "Topical N-acetyl cysteine and genistein prevent ultraviolet-light-induced signaling that leads to photoaging in human skin in vivo", Journal of Investigative Dermatology, Vol. 120, No. 1, pp. 835-841, (2003).   DOI
19 S. H. Yoo, Studies of Physiological Activity of Wheat Sprout Extract Cosmetic material, Unpublished doctoral dissertation, Konkuk University, (2016).
20 M. G. L. Hetog, P. C. H. Hollman, "Van de Putte B: Content of potentially anticarcinogenic flavonoids of tea infusions, wines and fruit juice", Journal of Agric Food Chem, Vol. 41, No. 8, pp. 1242-1246, (1993).   DOI
21 J. Imai, N. Ide, S. Nagae, T. Moriguchi, H. Matsuura, Y. Itakura, "Antioxidant and radical scavenging effects of aged garlic extract and its constituents", Plant Med, Vol. 60, No. 5, pp. 417-420, (1994).   DOI
22 Y. J. Kim, Feed value Evaluation of by-products of Astragalus membranaceus Fermentation using effective microorganisms (In vitro) an emphasis on test, Unpublished Master's thesis, Kangwon University, (2016).
23 T. Wu, Annie, S. W. Bligh, L. H. Gu, Z. T. Wang, H. P. Liu, X. M. Cheng, C. J. Branford-White, Z. B. Hu, "Simultaneous determination of six isoflavonoids in commercial Radix Astragali by HPLCUV", Fitoterapia, Vol. 76, No. 1, pp. 157-165, (2005).   DOI
24 H. B. Xiao, M. Krucker, K. Albert, X. M. Liang, "Determination and identification of isoflavonoids in Radix astragali by matrix solid-phase dispersion extraction and high-performance liquid chromatography with photodiode array and mass spectrometric detection", Journal of Chromatography, Vol. 1032, No. 1, pp. 117-124, (2004).   DOI
25 J. Kim, C. W. Lee, E. K. Kim, S. J. Lee, N. H. Park, H. S. Kim, H. K. Kim, K. Char, Y. P. Y. P. Jang, J. W. Kim, "Inhibition effect of Gynura procumbens extract on UV-B-induced matrix-metalloproteinase expression in human dermal fibroblasts", Journal of Ethnopharmacology, Vol. 137, No. 1, pp. 427-433, (2011)   DOI
26 J. S. Kim, Analysis of constituents of Astragali radix by HPLC/ELSD, Unpublished Master's thesis, Seoul University, (1998).
27 E. J. Kim, K. S. Yang, "Effect of Astragali Radix on low density lipoprotein oxidation", Yakhak Hoeji, Vol. 45, No. 1, pp. 529-535, (2001).
28 S. K. Park, Studies on the proteome profiling for anti-aging efficacy of polypeptides from Astragalus membranaceus Bunge, Unpublished Master's thesis, Woosuk University, (2015).
29 B. Havsteen, "Flavonoids, a class of natural products of high pharmacological potency, Biochemical Pharmacology", Vol. 32, No. 1, pp. 1141-1148, (1983).   DOI
30 Y. J. Lee, Comparison of Phenolic Compounds, Astragalosides, Soyasapogenol, and Vitamin E Contents with Extraction Methods and Solvents in Different Regions and Cultivated Years of Astragalus membranaceus, Unpublished Master's thesis, Konkuk University, (2013).
31 C. H. Hong, Effect of Astragali Radix Pharmacocupuncture on Wound Healing of Full-thickness Skin Wounds in Mouse, Unpublished Master's thesis, Dongeui University, (2015).