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http://dx.doi.org/10.12925/jkocs.2021.38.1.309

The Study on the Physiological Activities of Beta vulgaris such as Antioxidant and Anti-inflammatory in RAW 264.7 cells  

Ji, Joong-Gu (Department of Herbal Health & Pharmacy, Joongbu University)
Publication Information
Journal of the Korean Applied Science and Technology / v.38, no.1, 2021 , pp. 309-317 More about this Journal
Abstract
This study was designed to examine the cell cytotoxic, anti-inflammatory, and antioxidant activity for raw material of Beta vulagaris tea. Antioxidative ability was evaluated by bioassays using DPPH and ABTS radical scavenging activity. Cell viability was assessed by MTT assay using RAW 264.7 cells, and investigated production levels of reactive oxide speies, and inflammatory meditors(i.e., nitric oxide, tumor necrosis factor-α, and interleukin-6) in LPS-induced RAW 264.7 cells. As a results, DPPH and ABTS raidcal scavenging activity were increased in a dose-dependent manner, and confirmed no cytotoxicity in all concentration. Also, it was significantly decreased level of ROS, NO, IL-6, and TNF-a in LPS-induced RAW 264.7 cells. Therefore these results suggest Beta vulagaris has considerable potential as a raw material of leached tea with safe anti-oxidative and anti-inflammatory effects.
Keywords
Beta vulagaris; Beta bulagaris leaching tea; physiological activities; antioxidant; anti-inflammatory;
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