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http://dx.doi.org/10.12925/jkocs.2020.37.2.162

Effects of Mung Bean (Phaseolus aureus L.) on Blood Glucose and Lipid Composition Improvement in Streptozotocin-induced Diabetic Rats  

Bark, Si-Woo (Department of Food Science and Technology, Pusan National University)
Kim, Han-Soo (Department of Food Science and Technology, Pusan National University)
Publication Information
Journal of the Korean Applied Science and Technology / v.37, no.2, 2020 , pp. 162-172 More about this Journal
Abstract
The purpose of this study was to investigate the improvement effect of 5% mung bean (phaseolus aureus L.) on the blood glucose and lipid metabolism function of streptozotocin (STZ, 45 mg/kg body weight)-induced diabetic rats. Seven-week-old male rats were divided into four groups (n=6), and fed experimental diets containing mung bean meal [basal diet+5% mung bean (BM), basal diet+STZ+5% mung bean (SM)], and control (BD), BS groups (basal diet+STZ). The results of this study, mung bean diet groups (BM, SM) in lipid composition evidenced the significantly reduction of serum total cholesterol, low density lipoprotein-cholesterol (LDL-cholesterol), atherosclerotic index (AI), cardiac risk factor (CRF), triglyceride (TG), phospholipid (PL), free cholesterol, cholesteryl ester, uric acid, blood glucose, non esterified fatty acid (NEFA), and elevation of high density lipoprotein-cholesterol (HDL-cholesterol). The serum albumin/globulin ratio (A/G ratio) was increased in mung bean supplementation diet than STZ-induced diabetic rats (p<0.05). Concentrations of sodium (Na) and chlorine (Cl) in sera were lower in the mung bean diet than diabetic group. Total calcium (T-Ca), phosphorus (Pi) and potassium (K) concentrations in sera were higher in the BM, SM and BD groups than BS group. In vivo experiments with Sprague-Dawley rats showed that ingestion of mung bean (phaseolus aureus L.) were effective in blood glucose and lipid composition.
Keywords
Mung bean (Phaseolus aureus L.); Blood glucose; Lipid composition; Non esterified fatty acid; Albumin/globulin ratio; Electrolyte;
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