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http://dx.doi.org/10.12925/jkocs.2020.37.1.7

Comparison on Anti-oxidant Effects of Pigment Extracts from Fabaceae 5 species  

Kim, ye-Ran (Department of Clinical Laboratory Science, College of Medical Sciences, Daegu Haany University)
Chang, Kyung-Soo (Department of Clinical Laboratory Science, College of Health Sciences, Catholic University of Pusan)
Chang, Jeong Hyun (Department of Clinical Laboratory Science, College of Medical Sciences, Daegu Haany University)
Publication Information
Journal of the Korean Applied Science and Technology / v.37, no.1, 2020 , pp. 7-16 More about this Journal
Abstract
The Fabaceae family are being used as traditional medicine. The aim of this study was to compare the antioxidant effects as well as the cell protecting effects of extracts of 5 species (Astragalus membranaceus, Caesalpinia sappan L., Glycyrrhiza uralensis F., Pueraria lobate O., Pterocarpus santalinus L.) in Fabaceae family. The extracts from 5 species were tested by radical scavenging activity test, total phenolic contents and the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay on human liver carcinoma (HepG2) cell line. Anti-oxidant effects of the extracts (5 mg/mL) from C. sappan was 93.49% by radical scavenging activity test. In addition, A. membranaceus extracts showed a weak radical scavenging activity. Anti-oxidant effects of the extracts (5 mg/mL) from A. membranaceus was 7.83% by radical scavenging activity test. Total phenolic contents of the extracts from C. sappan and A. membranaceus were 310.93 mg GAE/g extract, 15.33 mg GAE/g extract, respectively. Cell protecting effects against H2O2 treatment were observed at 100 ㎍/mL concentration of C. sappan and P. santalinus extracts. These results suggest that C. sappan and P. santalinus might be best anti-oxidant in Fabaceae family.
Keywords
Anti-oxidants; radical scavenging activity; Total phenolic contents; Cell protecting effects; Fabaceae Family;
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