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http://dx.doi.org/10.12925/jkocs.2019.36.4.1485

Study on the Antioxidant and Anti-inflammatory Effects of Extracts of Callus Cultures, pericarp, flesh, fruit of Trapa Japonica  

Jang, Hye In (School of Cosmetic Science and Beauty Biotechnology, Semyung University)
Publication Information
Journal of the Korean Applied Science and Technology / v.36, no.4, 2019 , pp. 1485-1495 More about this Journal
Abstract
The purpose of this study was to evaluate the antioxidant and anti-inflammatory effects of extracts of callus cultures, pericarp, flesh, fruit of Trapa Japonica. The toxicity of extracts from Trapa Japonica pericarp investigated using the RAW 264.7 cell showed 45.8 ± 1.5% of cell survival rate. And the results of investigation using HaCaT cells showed a 51.1 ± 1.0% cell viability at 100 ㎍/㎖ in the pericarp extract and lower cell viability at higher concentrations. The total content of polyphenol pericarp extract was 213.20 ± 15.78 mg/g, while the total content of flavonoid was 29.30 ± 3.24mg. And the total content of polyphenol callus cultures extract was 205.20 ± 18.97 mg/g, while the total content of flavonoid was 237.4 ± 7.43 mg. With a concentration level of 0.005 ~ 1000 ㎍/㎖ extract of Trapa Japonica pericarp the range of removal of 1, 1-diphenyl-2-picryl-hydrazyl (DPPH) radicals was 67.53 ± 1.5 % ~ 75.75 ± 0.5 % respectively and the range of removal of extract of Trapa Japonica callus cultures extract was also 3.1 ± 0.1 % ~ 77.32 ± 0.5 % respectively. As a result of measuring the Nitric Oxide(NO) generation amount of all Trapa Japonica extract 6.25, 12.5, 25, 50 ㎍/㎖ concentration exhibited significant (p < 0.05, p < 0.01) decreases.
Keywords
Trapa Japonica Flesh; Trapa Japonica Pericarp; Trapa Japonica Callus cultures; Antioxidant; Anti-inflammatory;
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1 Matsumura and H. N. Ananthaswamy, "Toxic effects of ultraviolet radiation on the skin", Toxicology and Applied Pharmacology, Vol.195, No.3 pp. 298, (2004).   DOI
2 Noel W, Raes G, Hassanzadeh Ghassabeh G, De Baetselier P, Beschin A, "Alternatively activated macrophages during parasite infections", Trends in Parasitology, Vol.20 pp. 126-133, (2004).   DOI
3 Mosser DM, Edwards JP, "Exploring the full spectrum of macrophage activation", Nature Reviews Immunology, Vol.8, pp.958-969, (2008).   DOI
4 S. J. An, H. O. Pae, G. S. Oh, B. M. Choi, S. Jeong, S. I. Jang, H. Oh, T. O. Kwon, C. E. Song, H. T. Chung, "Inhibition of TNF-${\alpha}$, IL-1${\beta}$, and IL-6 productions and NF-${\kappa}B$ activation in lipopolysaccharide-activated RAW 264.7 macrophages by catalposide, an iridoid glycoside isolated from Catalpa ovata G. Don (Bignoniaceae)", International Immunopharmacology, Vol.2, pp. 1173-1181, (2002).   DOI
5 W. K. Alderton, C. E. Cooper, R. G. Knowles, "Nitric oxide synthases: structure, function and inhibition", Biochemical Journal, Vol.357, Pt3 pp. 593-615, (2001).   DOI
6 D. J. Lee, O. H. Lee, G. P. Choi, J. D. Kim, "Antioxidant and Anti-Adipogenic Activities of Trapa japonica Shell Extract Cultivated in Korea", Preventive nutrition and food science, Vol.22, No.4, pp. 327-334, (2017).   DOI
7 M. J. Kang, S. K. Lee, J. H. Song, M. E. Kim, M. J. Kim, J. I. Kim, J. S. Jang, J. H. Lee, "Water Chestnut (Trapa japonica Flerov.) Exerts Inhibitory Effect on Postprandial Glycemic Response in Rats and Free Radical Scavenging Activity in vitro", Food science and biotechnology, Vol.18, No.3, pp. 808-812, (2009).
8 A. J. Parr, K. W. Waldron, A. Ng, M. L. Parker, "The Wall-Bound Phenolics of Chinese Water Chestnut (Eleocharis dulcis)", Journal of the Science of Food and Agriculture, Vol.71, No.4, pp. 501-507, (1996).   DOI
9 S. Mariathasan, D. M. Monack, "Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation", Nature Reviews Immunology, Vol.7, No.1, pp. 31-40, (2007).   DOI
10 H. S. Kwon, J. H. Park, D. H. Kim, Y. H. Kim, H. K. Shin J. K. Kim. "Licochalcone A isolated from licorice suppresses lipopolysaccharide-stimulated inflammatory reactions in RAW264.7 cells and endotoxin shock in mice". Journal of Molecular Medicine, Vol.86, No. 11, pp. 1287-1295, (2008).   DOI
11 Y. S. Kim, J. W. Hwang, Y. K. Han, H. J. Kwon, H O. Hong, E. H. Kim, S. H. Moon, B. T. Jeon, P. J. Park, "Antioxidant activity and protective effects of Trapa japonica pericarp extracts against tert-butylhydroperoxide-induced oxidative damage in Chang cells". Food and Chemical Toxicology, Vol.64, pp. 49-56, (2014).   DOI
12 S.-H. Kim, H. Jeong, Y.-K. Kim, S.-H. Cho, K.-U. Min, Y.-Y. Kim, "IgE-mediated occupational asthma induced by herbal medicine, Banha (Pinellia ternata)", Clinical Experimental Allergy, Vol.31, No.5 pp. 779-781, (2001).   DOI
13 S. Zedler, E. Faist, "The impact of endogenous triggers on trauma-associated inflammation", Current Opinion in Critical Care, Vol.12, No.6, pp. 595-601, (2006).   DOI
14 H. M. Han, Y. S. Kwon, M. J. Kim, "Antioxidant and Antiproliferative Activity of Extracts from Water Chestnut (Trapa japonica Flerow)", Korean Journal of Medicinal Crop Science, Vol.24, No.1, pp. 14-20, (2016).   DOI
15 H. I. Jang, "Study on the antioxidant, anti-inflammatory and Preservative features Water Chestnut", Journal of Oil & Applied Science, Vol.35, No.3, pp. 633-642, (2018).   DOI
16 B. R Kim, J. E. Kim, B. K. Choi, H. S. Kim, "Anti-Inflammatory Effects of Water Chestnut Extract on Cytokine Responses via Nuclear Factor-${\kappa}B$-signaling Pathway", Biomol Ther (Seoul). Vol.23, No.1 pp. 90-97, (2015).   DOI
17 J. J. Nam, Y. J. Ki, "Fractionated Trapa japonica Extracts Inhibit ROS-induced Skin Inflammation in HaCaT keratinocytes", Journal of Society Cosmetic Science. Korea, Vol.41, No.1, pp. 45-55, (2015).   DOI
18 Y. S. Kim, J. W. Hwang, J. H. Jang, S. K. Son, I. B. Seo, J. H. Jeong, E. H. Kim, S. H. Moon, B. T. Jeon, P. J. Park, "Trapa japonica Pericarp Extract Reduces LPS-Induced Inflammation in Macrophages and Acute Lung Injury in Mice", Molecules, Vol.21, pp. 392-408, (2016).   DOI
19 J. J. Nam, K. E. Lee, J. E. Park, S. J Moon, J. K. Youm, "Inhibitory Effect of Fractionated Trapa Japonica Extracts on UVB-induced Skin Photoaging", Journal of Society Cosmetic Science. Korea, Vol.40, No.4 pp. 321-330, (2014).   DOI
20 Dicosmo, F, Misawa, M, "Plant cell and tissue culture: Alternatives for metabolite production", Biotechnology Advances. Vol.13, No.3, pp. 425-453, (1995).   DOI
21 M. U. Kim, "Optimization of suspension cultivatation of Aloe vera callus and characteristics of cultured products from suspension culture", Kangwon University, (2011).
22 I. S. Kim, "Characteristics of cells derived from Artemisia annua L. cambium and anti-inflammatory activity of cell extracts", Jeonbuk Univerity, (2011).
23 Gutfinger T. Polyphenols in olive oils. Journal of the American Oil Chemists Society, Vol. 58, No.11, pp. 966-968, (1981).   DOI
24 MI Moreno, MI Isla, AR Sampietro ,MA Vattuone."Comparison of the free radical-scavenging activity of propolis from several regions of Argentina", Journal of ethnopharmacology. Vol.71, No.1, pp. 109, (2000).   DOI
25 H. J. Lee, B. Y. Sim. J. W. Bak, D. H. Kim, "Effect of Gami-sopungsan on inflammation and DNCB-induced dermatitis in NC/ Nga in mice. Korean Journal of Oriental Physiology & Pathology, Vol.28, No.2 pp.146-153, (2014).
26 C. Gabay, "Interleukin-6 and chronic inflammation", Arthritis Research & Therapy, Vol.8, S2, (2006).
27 D. Y. Im, "Volatile compounds analysis of the extract from dried bark of Prunus sargentii and physiological activity of the main compound, benzaldehyde", Asian Journal of Beauty and Cosmetology, Vol.12, pp 155-162, (2014)
28 J. J. Van Triel, J. H. Arts, H. Muijser, C. F. Kuper, "Allergic inflammation in the upper respiratory tract of the rat upon repeated inhalation exposure to the contact allergen dinitrochlorobenzene (DNCB)", Toxicology, Vol.269, pp. 73-80, (2010).   DOI