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http://dx.doi.org/10.12925/jkocs.2019.36.2.434

Stabilization of Nanoemulsion Using PEG-free Surfactant  

Kim, Huiju (Department of Chemistry and Cosmetics, College of National Science, Jeju National University)
Jung, Taek Kyu (Skin Science R&D Center, Saimdamg Cosmetics, Co., Ltd.)
Kim, Ja Young (Skin Science R&D Center, Saimdamg Cosmetics, Co., Ltd.)
Yoon, Kyung-Sup (Department of Chemistry and Cosmetics, College of National Science, Jeju National University)
Publication Information
Journal of the Korean Applied Science and Technology / v.36, no.2, 2019 , pp. 434-447 More about this Journal
Abstract
Polyethylene glycol (PEG) is widely used in cosmetics as a surfactant, detergent and emulsifier. During the manufacturing process, 1,4-dioxane, which is toxic to humans, can be produced as a by-product by dimerization of ethylene oxide. As consumers' interest in cosmetic ingredients has increased, the need for safe emulsion research without PEG ingredients in the personal care market has increased. With increasing consumer interest in cosmetic ingredients, the need for safer emulsion research without the PEG ingredient in the personal care market has increased. In this study, we aimed to develop and stabilize nanoemulsion formulation without PEG. Response Surface Methodology (RSM) was used to develop optimized nanoemulsion formulations. Surfactant content (2~4%), oil content (4~8%) and polyol content (12~24%) were set as independent variables as a result of preliminary experiments for determining independent variables and ranges. The particle size, zeta potential, turbidity, and polydispersity index of the formulation were measured as response variables. As a result of measurement of the prepared nanoemulsion by FIB (Focused ion beam), spherical particles were found to have a size distribution of 100 to 200 nm. The stability of each formulation was evaluated for 30 days at each temperature ($4^{\circ}C$, $25^{\circ}C$, and $45^{\circ}C$). The optimal formulation considering the optimum particle size, turbidity, polydispersity index and zeta potential was found to be surfactant (2%), oil (8%) and polyol (24%).
Keywords
Nanoemulsion; PEG-free; RSM (Response Surface Methodology); FIB (Focused ion beam); Polyglycerol ester;
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Times Cited By KSCI : 3  (Citation Analysis)
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