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http://dx.doi.org/10.12925/jkocs.2019.36.1.47

Effects of Turmeric (Curcuma longa L.) on Lipid Component and Protein Concentration in Dyslipidemic Rats  

Oh, Da-Young (Department of Food Science and Technology, Pusan National University,)
Kang, Dong-Soo (1Department of Marine Bio Food Science, Chonnam National University,)
Lee, Young-Geun (Department of Food Science and Technology, Pusan National University,)
Kim, Han-Soo (Department of Food Science and Technology, Pusan National University,)
Publication Information
Journal of the Korean Applied Science and Technology / v.36, no.1, 2019 , pp. 47-58 More about this Journal
Abstract
This study aimed to investigate the improvement effect of turmeric (Curcuma longa L.) on the lipid component, protein and electrolyte concentration in dyslipidemic rats. Sprague-Dawley rats (24 male) were divided into four groups, namely the ND (normal-nondyslipidemic diet), NT (normal-nondyslipidemic diet+5% turmeric), DD (control-dyslipidemic diet), and DT groups (dyslipidemic diet+5% turmeric). Rats were sacrificed at the end of 5 weeks after experiment diet. In this study, turmeric diet (NT, DT) groups in lipid composition as evidenced from the significantly reduction of serum total cholesterol, low density lipoprotein-cholesterol (LDL-cholesterol), atherosclerotic index (AI), cardiac risk factor (CRF), triglyceride (TG), phospholipid (PL), free cholesterol, cholesteryl ester, blood glucose and non esterified fatty acid (NEFA), and elevation of high density lipoprotein-cholesterol (HDL-cholesterol) (p<0.05). The serum globulin concentration was significantly decreased (p<0.05), and the albumin concentrations were increased in turmeric diet than dyslipidemic rats. Concentrations of sodium (Na) and chlorine (Cl) in sera were lower in the DT group than DD group. Concentrations of total calcium (T-Ca), phosphorus (Pi) and potassium (K) in sera were higher in the ND, NT and DT groups than DD group. Therefore, it was concluded that the 5% turmeric diet used in the condition of this study had a beneficial effect on dyslipidemia.
Keywords
Turmeric (Curcuma longa L.); Lipid metabolism; Albumin; Globulin; Electrolyte;
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