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http://dx.doi.org/10.12925/jkocs.2019.36.1.34

The effect of swimming plus hypolipidemic agent on obesity  

Jeong, Sun-Hyo (Division of Biomedical Engineering & Health, Science Management, Mokwon University)
Publication Information
Journal of the Korean Applied Science and Technology / v.36, no.1, 2019 , pp. 34-46 More about this Journal
Abstract
Obesity is frequently associated with metabolic disease. This study showed whether fenofibrate, a hypolipidemic agent, swimming and swimming combined with fenofibrate (: combination) regulate obesity, and whether combination is more effective than fenofibrate on regulation of obesity in high-fat diet-fed mice for 8 weeks. Both fenofibrate and swimming decreased obesity-associated factors such as body weight, adipose tissue mass, serum lipid levels and adipoctye size, compared with control mice. When mice were concomitantly treated with fenofibrate and swimming, combination reduced further the inhibitory effects on obesity-associated factors, compared with fenofibrate. Both fenofibrate, swimming and combination decreased serum glucose levels, compared with control mice. The evidence is presented herein that combination were effective to control obesity and serum glucose levels, suggesting that swimming combined with fenofibrate might contribute to inhibition of high-fat diet fed-induced metabolic syndrome.
Keywords
obesity; fenofibrate; swimming; body weight; adipose tissue mass;
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