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http://dx.doi.org/10.12925/jkocs.2018.35.4.1320

Antioxidant and Neuronal cell protective effects of Stachys sieboldii Miq. according to drying methods  

Oh, Hee-Kyung (Department of Bio-animal care, Jangan University)
Publication Information
Journal of the Korean Applied Science and Technology / v.35, no.4, 2018 , pp. 1320-1326 More about this Journal
Abstract
This study investigated the antioxidant and neuronal cell protective effects of activity of water and 70% ethanol extracts from Stachys sieboldii Miq. according to different drying method(hot air drying and freeze-drying). The total flavonoid and total polyphenol content in water extracts was significantly higher after freeze-drying compared to hot air drying(p<0.05). DPPH and ABTS radical scavenging were increased in a dose-dependent manner. The DPPH and ABTS radical scavenging activity of water extract were significantly higher after free-drying compared to hot air drying(p<0.05). In a cell viability using MTT, the water extract according to hot air drying and freeze-drying of Stachys sieboldii Miq. showed protective effect against H2O2-induced nurotoxicity. The results suggest that the water extracts of Stachys sieboldii Miq. after freeze-drying has antioxidant activities and may be useful for neurodegenerative disorders.
Keywords
Stachys sieboldii Miq; freeze-drying; Total flavonoid; antioxidant effect; neuronal cell protective effect;
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