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http://dx.doi.org/10.12925/jkocs.2018.35.3.826

Effects of Various Sodium Fluoride (NaF) Administration on Blood Glucose, Lipid Composition and A/G Ratio in Rats  

Kim, Han-Soo (Department of Food Science and Technology, Pusan National University)
Publication Information
Journal of the Korean Applied Science and Technology / v.35, no.3, 2018 , pp. 826-835 More about this Journal
Abstract
The aim of the study was to investigate the influences of sodium fluoride on the body weight, lipid metabolism functional improvement, blood glucose level, protein component in the sera of rats which fed experimental diets for 5 weeks. Body weight gain of rats was higher in the NF25 group, NF30 group and NF50 group showed a significant difference from the basal diet group (BD group). The changes of the liver and the heart of each argan weights were observed compared to the BD group tends to appear lower in the oral NaF groups (p<0.05). Organ weight of each group of the others showed no significant difference (p<0.05). Serum concentrations of total cholesterol, low-density lipoprotein (LDL)-cholesterol, free cholesterol, triglyceride (TG), phospholipid (PL) and blood glucose were lower in BD group than basal diet plus sodium fluoride groups. Conversely depending on the concentration of sodium fluoride for the high-density lipoprotein (HDL)-cholesterol level, it showed lower results. Serum total protein was observed low showed a significant difference in the NF50 group, there was no significant difference in the other groups (p<0.05). globulin and albumin concentration levels also showed the lowest results in the NF50 group.
Keywords
Sodium fluoride; Lipid level; Blood glucose; Albumin; Globulin;
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