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http://dx.doi.org/10.12925/jkocs.2017.34.3.602

Study on Applicability of Pinus koraiensis Siebold et Zucc Leaf Extract as a Cosmetic Ingredient  

Jeon, Myung-Ok (Department of Bioengineering, Konkuk University)
Moon, Ji-sun (Department of Beauty Health, Jungwon University)
Publication Information
Journal of the Korean Applied Science and Technology / v.34, no.3, 2017 , pp. 602-612 More about this Journal
Abstract
This study was performed to verify various effects of 70% ethanol extract and distilled water extract of pine leaf such as antioxidant, anti-inflammatory, skin-lightening effects analysis in cells. The result of antioxidant experiment showed that polyphenol content increased concentration dependently in polyphenol and flavonoid effects. The total content of polyphenols and flavonoids was much higher in ethanol extract than water extract. In all the cells of B16F10, RAW264.7 cytotoxicity at each concentration level didn't appear. The result of measuring NO production inhibition showed that it inhibited NO production led to LPS effectively, so anti-inflammatory activity was confirmed. The result of measuring melanin biosynthesis inhibition showed that there was considerably reduction effect, but it performed western blot, and as a result of MITF, Tyrosinase protein revelation, the inhibition of MITF, Tyrosinase revelation was confirmed concentration dependently, Therefore, in this study pine leaf extract was expected to be used as a cosmetic ingredient.
Keywords
Pinus koraiensis leaf; Anti-inflammation; Anti-oxidant; Whitening; Cosmetic material;
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