Browse > Article
http://dx.doi.org/10.12925/jkocs.2017.34.2.244

Evaluation of Lipid Peroxidation Inhibition and Nitrogen Oxide Scavenging Activity from Peel of Gardenia jasminoides Ellis Fructus Extracted by Various Solvents  

Jin, Dong-Hyeok (Department of Food Science and Technology, Pusan National University)
Oh, Da-Young (Department of Food Science and Technology, Pusan National University)
Chung, Hun-Sik (Department of Food Science and Technology, Pusan National University)
Lee, Young-Guen (Department of Food Science and Technology, Pusan National University)
Seong, Jong-Hwan (Department of Food Science and Technology, Pusan National University)
Kim, Han-Soo (Department of Food Science and Technology, Pusan National University)
Publication Information
Journal of the Korean Applied Science and Technology / v.34, no.2, 2017 , pp. 244-253 More about this Journal
Abstract
The aim of this study was to investigate the bioactivity and antioxidant activity of peel from Gardenia jasminoides Ellis fructus (GJE). We were separated into GJE peel. After that, we determined anthocyanin. GJE peel were extracted by 70% methanol, distilled water (DW) and ethyl acetate (EA) three solvents. To investigate by the solvent extract of total phenol content and value as a functional food ingredient of GJE peel through nitrogen oxide scavenging activity, antioxidant activity, reducing power and lipid peroxidation inhibition were performed. Solvent extract bioactivity of increasing concentrations (0.2, 0.4, 0.6 mg/mL) were significantly increased (p<0.05). GJE peel extracts showed lower activity than positive control (ascorbic acid, BHA, trolox). The total phenol contents of GJE peel extracts were highest in EA extract. However, the order of total phenol content of the solvent in the GJE peel and the results of analysis of various physiological activities were inconsistent. Considering the extraction yield and various physiological activities, it is expected to be effective when extracted from 70% methanol and DW extract. The results suggest that GJE peel is highly expected to be useful as a functional foods and natural antioxidant.
Keywords
Peel of Gardenia jasminoides Ellis fructus; Solvent extracts; Antioxidant activity; Anthocyanin; Total phenol;
Citations & Related Records
Times Cited By KSCI : 3  (Citation Analysis)
연도 인용수 순위
1 Y. Yamamoto, M. H. Brodsky, J. C. Baker and B. N. Ames, "Detection and characterization of lipid hydroperoxides at picomole levels by high-performance liquid chromatography", Anal. Biochem., Vol.160, No.1 pp.7-13 (1987).   DOI
2 H. Esterbauer, "Cytotoxicity and genotoxicity of lipid-oxidation products", American J. Clin. Nutr., Vol.57, No.5 pp.779S-785S (1993).   DOI
3 D. H. Jin, H. S. Kim, J. H. Seong and H. S. Chung, "Comparison of total phenol, flavonoid contents, and antioxidant activities of Orostachys japonicus A. Berger extracts", J. Environ. Sci. Int., Vol.25, No.5 pp.695-703 (2016).   DOI
4 J. Kearney, "Food consumption trends and drivers", Philosoph. Transact. Royal Soc. B: Biol. Sci., Vol.365, No.1554 pp.2793-2807 (2010).   DOI
5 K. Menrad, "Market and marketing of functional food in Europe", J. Food Eng., Vol.56, No.2 pp.181-188 (2003).   DOI
6 H. O. Edeoga, D. E. Okwu and B. O. Mbaebie, "Phytochemical constituents of some Nigerian medicinal plants", African J. Biotechnol., Vol.4, No.7 pp.685-688 (2005).   DOI
7 B. Halliwell, J. M. Gutteridge and C. E. Cross, "Free radicals, antioxidants, and human disease: where are we now?", J. Lab. Clinic. Med., Vol.119, No.6 pp.598-620 (1992).
8 N. Hogg, V. M. Darley-Usmar, M. T. Wilson and S. Moncada, "Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide". Biochemical Journal, Vol.281, No.2 pp.419-424 (1992).   DOI
9 J. S. Hwang, B. H. Lee, X. An, H. R. Jeong, Y. E. Kim, I. Lee, H. Lee and D. O. Kim, "Total phenolics, total flavonoids, and antioxidant capacity in the leaves, bulbs, and roots of Allium hookeri", Korean J. Food Sci. Technol., Vol.47, No.2 pp.261-266 (2015).   DOI
10 I. A. Lee, J. H. Lee, N. I. Baek and D. H. Kim, "Antihyperlipidemic effect of crocin isolated from the fructus of Gardenia jasminoides and its metabolite crocetin", Biol. Pharm. Bull., Vol.28, No.11 pp.2106-2110 (2005).   DOI
11 J. A. Lim, Y. S. Na and S. H. Baek, "Antioxidative activity and nitrite scavenging ability of ethanol extract from Phyllostachys bambusoides", Korean J. Food Sci. Technol., Vol.36, No.2 pp.306-310 (2004).
12 T. Fuleki and F. J. Francis, "Quantitative methods for anthocyanins", J. Food Sci., Vol.33, No.3 pp.266-274 (1968).   DOI
13 T. Sun and C. T. Ho, "Antioxidant activities of buckwheat extracts", Food Chem., Vol.90, No.4 pp.743-749 (2005).   DOI
14 M. N. A. Rao, "Nitric oxide scavenging by curcuminoids", J. Pharm. Pharmacol., Vol.49, No.1 pp.105-107 (1997).   DOI
15 T. A. Holton and E. C. Cornish, "Genetics and biochemistry of anthocyanin biosynthesis", The Plant Cell, Vol.7, No.7 pp.1071 (1995).   DOI
16 S. Kato, H. Aoshima, Y. Saitoh and N. Miwa, "Highly hydroxylated or $\gamma$-cyclodextrin-bicapped water-soluble derivative of fullerene: The antioxidant ability assessed by electron spin resonance method and $\beta$-carotene bleaching assay", Bioorg. Med. Chem. Lett., Vol.19, No.18 pp.5293-5296 (2009).   DOI
17 M. Singhal, A. Paul and H. P. Singh, "Synthesis and reducing power assay of methyl semicarbazone derivatives", J. Saudi Chem. Soc., Vol.18, No.2 pp.121-127 (2014).   DOI
18 N. Siriwardhana, K. W. Lee, Y. J. Jeon, S. H. Kim and J. W. Haw, "Antioxidant activity of Hizikia fusiformis on reactive oxygen species scavenging and lipid peroxidation inhibition", Food Sci. Technol. Int., Vol.9, No.5 pp.339-346 (2003).   DOI
19 Z. Lin, J. Fischer and L. Wicker, "Intermolecular binding of blueberry pectin-rich fractions and anthocyanin", Food Chem., Vol.194, pp.986-993 (2016).   DOI
20 A. Sgambato, R. Ardito, B. Faraglia, A. Boninsegna, F. I. Wolf and A. Cittadini, "Resveratrol, a natural phenolic compound, inhibits cell proliferation and prevents oxidative DNA damage", Mutat. Res. Genet. Toxicol. Environ. Mutagen., Vol.496, No.1 pp.171-180 (2001).   DOI
21 D. Pastore, D. Trono, L. Padalino, S. Simone, D. Valenti, N. Di Fonzo and S. Passarella, "Inhibition by $\alpha$-tocopherol and L-ascorbate of linoleate hydroperoxidation and ${\beta}$-carotene bleaching activities in durum wheat semolina", J. Cereal Sci., Vol.31, No.1 pp.41-54 (2000).   DOI
22 Y. Cai, Q. Luo, M. Sun and H. Corke, "Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer", Life Sci., Vol.74, No.17 pp.2157-2184 (2004).   DOI
23 R. Re, N. Pellegrini, A. Proteggente, A. Pannala, M. Yang and C. "Rice-Evans, Antioxidant activity applying an improved ABTS radical cation decolorization assay", Free Radical Biol. Med., Vol.26, No.9 pp.1231-1237 (1999).   DOI
24 S. R. M. J. Moncada, R. M. L. Palmer and E. Higgs, "Nitric oxide: physiology, pathophysiology, and pharmacology", Pharmacol. Rev., Vol.43, No.2 pp.109-142 (1991).
25 S. H. Snyder and D. S. Bredt, "Biological roles of nitric oxide", Sci. American, Vol.266, No.5 pp.68-77 (1992).   DOI
26 H. Moshage, B. Kok, J. R., Huizenga and P. L. Jansen, "Nitrite and nitrate determinations in plasma: a critical evaluation", Clin. Chem., Vol.41, No.6 pp.892-896 (1995).
27 M. Senevirathne, S. H. Kim, N. Siriwardhana, J. H. Ha, K. W. Lee and Y. J. Jeon, "Antioxidant potential of ecklonia cavaon reactive oxygen species scavenging, metal chelating, reducing power and lipid peroxidation inhibition", Food Sci. Technol. Int., Vol.12, No.1 pp.27-38 (2006).   DOI
28 O. Firuzi, A. Lacanna, R. Petrucci, G. Marrosu and L. Saso, "Evaluation of the antioxidant activity of flavonoids by "ferric reducing antioxidant power" assay and cyclic voltammetry", Biochim. Biophys. Acta-Gen. Subj., Vol.1721, No.1 pp.174-184 (2005).   DOI
29 E. N. Frankel, "Lipid oxidation", Prog. Lipid Res., Vol.19, No.1 pp.1-22 (1980).   DOI