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http://dx.doi.org/10.12925/jkocs.2016.33.3.428

Effects of Benzyltrialkylammonium Type Cationic Surfactants on the Preparation and Properties of Liposome  

Jung, Yeonseok (Department of Engineering Chemistry, Chungbuk National University)
Jeong, Noh-Hee (Department of Engineering Chemistry, Chungbuk National University)
Publication Information
Journal of the Korean Applied Science and Technology / v.33, no.3, 2016 , pp. 428-434 More about this Journal
Abstract
In this study, benzyltrialkylammonium chlorides with different alkyl chain length were synthesized and applied to liposome. Prepared cationic surfactant embedded liposomes were measured particle size, zetapotential, release property and antibacterial activity. The average particle size of liposomes was 120~140 nm. As alkyl chain length was increased, the liposome size was increased. Zetapotential for the solution of liposomes added cationic surfactants were in the range of +80~90 mV. In release test, collagen release rate could be controlled by alkyl chain length. liposome embedded long alkyl chain surfactant had enhanced sustained release property. Entrapment efficiency of hydrophilic collagen were 25.9~27.5%.
Keywords
cationic surfactant; particle size; liposome; zeta potential; release property;
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Times Cited By KSCI : 1  (Citation Analysis)
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