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http://dx.doi.org/10.12925/jkocs.2016.33.2.361

Antioxidant Activities and Anti-aging Effects of Orostachys japonicus A. Berger Extracts  

Jung, Da-Jung (Department of Microbial Engineering, Konkuk University)
Choe, Tae-Boo (Department of Microbial Engineering, Konkuk University)
Publication Information
Journal of the Korean Applied Science and Technology / v.33, no.2, 2016 , pp. 361-373 More about this Journal
Abstract
This study tested the antioxidant activities and anti-aging effects of an extract of Orostachys japonicus, a herb used as a folk remedy for cancer for a long time. To assess the antioxidant activities of the Orostachys japonicus extract (OJE), the total polyphenol content was confirmed to have a high caffeic acid equivalent weight of 12 g by dry weight of 100g OJE and the total flavonoid content was confirmed that the quercetin equivalent of 1.7 g by dry weight of 100g OJE. DPPH free radical scavenging activity was confirmed a high scavenging activity of 79.7% at a concentration of 1%. To confirm the anti-aging effect of OJE, MMP-1 expression was decreased in $25{\mu}L/mL$ and $50{\mu}L/mL$ similar to control. In a clinical experiment, a group of subjects who used a cosmetic product containing OJE showed a significant increase in the amount of skin moisture from the forehead, left cheek, and chin. The experimental group showed a significant increase in the amount of skin sebum from the chin and maintaining pH balance of normal skin, As a result, the OJE demonstrates the efficacy of natural cosmetic material as antioxidant and anti-aging.
Keywords
Antioxidant; Anti-aging; Cosmetics; Orostachys japonicus;
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