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http://dx.doi.org/10.12925/jkocs.2016.33.1.41

Antioxidative Effects of Rhaphiolepis indica and Quercus salicina from Jeju  

Kim, Hye-Ran (Department of Clinical Laboratory Science, Catholic University of Pusan)
Park, Gyu-Nam (Department of Clinical Laboratory Science, Catholic University of Pusan)
Jung, Bo-Kyoung (Department of Clinical Laboratory Science, Catholic University of Pusan)
Yoon, Weon-Jong (Jeju Biodiversity Research Institute, Jeju Technopark)
Jung, Yong-Hwan (Jeju Biodiversity Research Institute, Jeju Technopark)
Chang, Kyung-Soo (Department of Clinical Laboratory Science, Catholic University of Pusan)
Publication Information
Journal of the Korean Applied Science and Technology / v.33, no.1, 2016 , pp. 41-50 More about this Journal
Abstract
In this study, the extracts from the leaves of Rhaphiolepis indica(R. indica) and Quercus salicina(Q. salicina) confirmed antioxidative effects. The antioxidative and cytotoxic effects of the two extracts were analyzed according to varied concentrations and time. The extracts of R. indica and Q. salicina showed dose-dependent DPPH radical scavenging activities. The extracts of R. indica and Q. salicina at concentrations of 5 mg/mL showed DPPH radical scavenging activities at 89.93 and 92.41%. Therefore, Q. salicina were confirmed to have higher antioxidative effects than R. indica. Total phenolic contents were 65.20 mg GAE/g for R. indica and 85.20 mg GAE/g for Q. salicina. The result that Q. salicina have higher total phenolic contents than R. indica suggested a correlation between total phenolic contents and DPPH radical scavenging activity. The cell protective effects of HepG2 and A549 cells under oxidative stress, both the extracts showed relatively low cell protective effects at around 10%. The Cytotoxic effects of A549 Cells did not show cytotoxicity at concentrations of $100{\mu}g/mL$ or below. The results of this study are likely to be used as basic data to develop antioxidants using the extract of R. indica and Q. salicina.
Keywords
Rhaphiolepis indica; Quercus salicina; antioxidative;
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