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http://dx.doi.org/10.12925/jkocs.2015.32.3.505

Whitening Effects of Arctigenin Extracted from the Arctii Fructus  

Kim, Tae-Hyeon (Department of Engineering Chemistry, College of Engineering Chungbuk National University Chemistry)
Park, Jong-Kwon (Department of Engineering Chemistry, College of Engineering Chungbuk National University Chemistry)
Jeong, Noh-Hee (Department of Engineering Chemistry, College of Engineering Chungbuk National University Chemistry)
Publication Information
Journal of the Korean Applied Science and Technology / v.32, no.3, 2015 , pp. 505-511 More about this Journal
Abstract
In this study, Arctigenin was obtained by using supercritical fluid extraction and bio-conversion process from Arctii Fructus. Arctigenin is efficacious in anti-inflammatory and anti-influenza. For this reason, Arctigenin is studied in various field. It was identified as 4-[(3,4-Dimethoxyphenyl)methyl)]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone (arctigenin) by FT-IR, $^1H$-NMR and the purity of it was 95.1 % by HPLC analysis. Arctigenin inhibited tyrosinase (up to $85.06{\pm}0.9%$ at $260{\mu}g/m{\ell}$ concentration) and melanin synthesis in a dose dependent manner (up to $51.1{\pm}3.7%$ at the concentration of $3.0{\mu}g/m{\ell}$). The results were better than arbutin. Therefore, it is expected that manufactured Arctigenin is useful for whitening cosmetics.
Keywords
Arctii Fructus; Arctigenin; Whiterning Effects; Cosmetic; Bioconversion;
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Times Cited By KSCI : 4  (Citation Analysis)
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