Browse > Article
http://dx.doi.org/10.12925/jkocs.2013.30.3.518

Study of Stabilizing 5,6-dihydroxyindole with Coating Process Against Oxidation and Light  

Han, Sang-Keun (Department of Industrial Engineering Chemistry, College of Engineering, Chungbuk National University)
Lee, Dong-Kyu (Department of Industrial Engineering Chemistry, College of Engineering, Chungbuk National University)
Publication Information
Journal of the Korean Applied Science and Technology / v.30, no.3, 2013 , pp. 518-527 More about this Journal
Abstract
5,6-dihydroxyindole was easily oxidation with air and light Conditions. Availability of 5,6-dihydroxyindole was studied for hair dye as a precursor of melanin. This study used wet and dry coating process to stabilize 5,6-dihydroxyindole. In wet process used dimethicone and cyclometicone, the 5,6-dihydroxyindole had darkened through the drying process at $58^{\circ}C$. Wet coating process was inappropriate to stabilize the coating. In dry coating process, shea butter coating was stable until 3 days. Dextrin palmitate was most efficient ingredient to prevent oxidation by sun light and air until 7days. Oxidation test with 1.0% and 1.5% of dextrin palmitate was not different under conditions of sun light and air and was not dependent on contents. Vitamin E acetate under conditions of sun light and air, there were no significant effect in preventing oxidation.
Keywords
5,6-dihydroxyindole; melanin; dye; hair care; dextrin palmitate;
Citations & Related Records
연도 인용수 순위
  • Reference
1 M. Cichorek, M. Wachulska, A. Stasiewicz, A. Tyminska, "Skin melanocytes : Biology and development", Postepy Dermatologiii Alergologii, 30, 30 (2013).
2 M. Balandrin, M. F., J. A. Klocke, E. S. Wurtele, and W. H. Bollonger, "Natural plant chemicals: Sources of industrial and medicinal materials", Science, 228, 1154 (1985).   DOI
3 L. Warwick, L. Morison, "What Is the Function of Melanin?", Arch Dermatol. 121(9), 1160-1163 (1985).   DOI
4 C. J. Vavricka, B. M. Christensen, J. Li, "Melanization in living organisms: A perspective of species evolution", J. of Protein and Cell, 1(9), 830 (2010).   DOI
5 N, Saino, M. Romano, "Viability Is Associated with Melanin-Based Coloration in the Barn Swallow (Hirundo rustica)", PLoS ONE, 4(4), e60426 (2013).
6 R. P. Shingh, S. sharad, S. Kapur. "Free Radicals and Oxidative Stress in Neurodegenerative Diseases : Relevance of Dietary Antioxidants", JIACM, 5(3), 218-25 (2004).
7 S. Commo, O. Gaillard, B. A. Bernard, "Human hair greying is linked to a specific depletion of hair follicle melanocytes affecting both the bulb and the outer root sheath", British J. of Dermatology, 150(3), 435 (2004).   DOI
8 H. M. Bolt, K. Golka, "The debate on carcinogenicity of permanent hair dyes: New insights", Crit. Rev. Toxicol., 37(6), 521 (2007).   DOI
9 E. K. Nishimura, etal.,"Mechanisms of hair graying: Incomplete melanocyte stem cell maintenance in the niche", Science, 5710, 720-4 (2005).
10 S. Kobayashi, H. Higashimura, "Oxidative polymerization of phenols revisited", Prog. Polym. Sci. 28. 1015-48 (2003).   DOI
11 S. Ito, K. Fujita, "Microanalysis of eumelanin and pheomelanin in hair and melanomas by chemical degradation and liquid chromatography", Anal. Biochem., 144(2), 527-36 (1985).   DOI
12 C. R. Borges, J. C. Roberts, D. G. Wilkins, D. E. Rollins, "Relationship of Melanin Degradation Products to Actual Melanin Content: Application to Human Hair", Anal. Biochemistry, 290, 116-25 (2001).   DOI
13 Mu-Ill Lim, Dilip G. Patil1, "Mushroom tyrosinase as an oxidant for the synthesis of 5,6-dihydroxyindole derivatives", Tetrahedron Lett.,28(33), 3775-8 (1987)   DOI
14 L. Novellino, M. d'Ischia, G. Prota, "Nitric oxide-induced oxidation of 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid under aerobic conditions: non-enzymatic route to melanin pigments of potential relevance to skin (photo)protection", Biochim Biophys Acta, 1425, 27-35 (1998).   DOI
15 J. J. Le Minez, B Schmitt. Wet-on-wet coating process, US Patent 4,375,498, (1983).