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http://dx.doi.org/10.12925/jkocs.2012.29.3.6

Antidiabetic Effect of Lonicerae Japonica Thunb Extract  

Kim, Ok-Kyung (Department of Food and Nutrition, Dae Jin University)
Shin, Sook-Ki (Department of Food and Nutrition, Dae Jin University)
Publication Information
Journal of the Korean Applied Science and Technology / v.29, no.3, 2012 , pp. 412-420 More about this Journal
Abstract
This study was carried out to investigate the antidiabetic effect of Lonicerae japonica Thunb(LJ) in the streptozotocin(STZ)-induced diabetic rats. The effective fractions were prepared as a form of organic solvents of hexane, chloroform, ethylacetate, butanol, water fractions prepared from the ethanol extract of LJ. The content of serum glucose and the activities of glucose-6-phosphatase(G-6-Pase) in the hexane and water fractions treated rats were significantly decreased compared to those of the STZ control group. Whereas the activity of hepatic glucose-6-phosphate dehydrogenase(G-6-PDH) was significantly increased in the hexane and water fractions treated rats. In conclusion, these results indicated that the hexane and water fractions of LJ were effective for the antidiabetes in the STZ-induced diabetic rats.
Keywords
streptozotocin; antidiabetic effect; Lonicerae japonica Thunb;
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