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http://dx.doi.org/10.12925/jkocs.2012.29.1.3

Crosslinking reaction system of polymers  

Ko, Jong-Sung (Korea Institute of Science and Technology Information)
Publication Information
Journal of the Korean Applied Science and Technology / v.29, no.1, 2012 , pp. 19-32 More about this Journal
Abstract
Pharmaceutical use accounts for a great part of articles and papers on crosslinking of polymers. Crosslinking of polymers used for tissue engineering and drug delivery respects non-cytotoxicity and in situ gelling. The crosslinking of polymers is aimed not only at the improvement of modulus, chemical resistance, and thermal resistance, but also at endowing them with such functions as metal adsorption, antifouling, and ion exchange via crosslinked segments. Smart polymers responding to environmental change, and cosslinking mediated by light, enzyme, natural compound and in aqueous medium in consideration of environment are being studied. Developing new polymeric materials is essential along with the pharmaceutics aiming at the longevity of 120 years old. Functionalization and property adjustment of polymers through crosslinking will be done more delicately. Hydrogels will be focused on injectable and in situ gel forming. In the coating industry crosslinking system with low non-toxicity and low energy consumption will be developed in consideration of workers and environment.
Keywords
crosslinking; hydrogel; click chemistry; in situ; drug delivery;
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  • Reference
1 Alex Adronov et al., "Pluronics as crosslinking agents for collagen: novel amphiphilic hydrogels", Polym Int, 60, 458 (2011).
2 Remzi Becer et al., "Synthesis of glycopolymers via click reactions", European Polymer Journal 47, 435 (2011).
3 Guillaume Tillet et al., "Chemical reactions of polymer crosslinking and post-crosslinking at room and medium temperature", Progress in Polymer Science 36, 191 (2011).
4 Gloria Huerta-Angeles et al., "Synthesis of highly substituted amide hyaluronan derivatives with tailored degree of substitution and their crosslinking via click chemistry", Carbohydrate Polymers 84, 1293 (2011).
5 Oommen P. Varghese et al., "Bone reservoir: Injectable hyaluronic acid hydrogel for minimal invasive bone augmentation", Journal of Controlled Release, 152, 232 (2011).
6 http://en.wikipedia.org/wiki/Hydrazone.
7 Timothy E. Long et al., "Michael addition reactions in macromolecular design for emerging technologies", Prog. Polym. Sci. 31, .487, (2006).
8 Christopher D. Pritchard, "An injectable thiol-acrylate poly(ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate", Biomaterials 32, 587 (2011).
9 Hong-Liang Wei et al., "Characterisation of N-vinyl-2-pyrrolidone-based hydrogels prepared by a Diels-Alder click reaction in water", European Polymer Journal, 46, 1032 (2010).
10 Ariel W. Chan, Ronald J. Neufeld, "Modeling the controllable pH-responsive swelling and pore size of networked alginate based biomaterials", Biomaterials 30, 6119 (2009).
11 Kuo Huang Hsieh ET AL., "Antibacterial activity and biocompatibility of a chitosan -${\gamma}$-poly(glutamic acid) polyelectrolyte complex hydrogel", Carbohydrate Research 345, 1774 (2010).
12 Kalyanee Sirisinha et al., "Comparison of techniques for determining crosslinking in silane-water crosslinked materials", Polymer Testing 25, 518 (2006).
13 Wankei Wan et al., "Synthesis, characterization and in vitro cell compatibility study of a poly(amic acid) graft/cross-linked poly(vinyl alcohol) hydrogel", Acta Biomaterialia 7, 258 (2011).
14 Sivanaga S. Anumolu, Anupa R. Menjoge, Manjeet Deshmukh, Donald Gerecke, Stanley Stein, Jeffrey Laskin, Patrick J. Sinko, "Doxycycline hydrogels with reversible disulfide crosslinks for dermal wound healing of mustard injuries", Biomaterials 32, 1204 (2011).
15 Sevil Savaskan Yimaz et al., "Synthesis of a novel crosslinked superabsorbent copolymer with diazacyclooctadecane crown ether and its sorption capability", European Polymer Journal 43, 1923 (2007).
16 Shaoyi Jiang et. al.,"Functionalizable and nonfouling zwitter ionic carboxybetaine hydrogels with a carboxybetaine dimethacrylate crosslinker", Biomaterials 32, 961 (2011).
17 Charlotte James, Thomas Pugh, Andrew L. Johnson, A. Tobias A. Jenkins, "An antimicrobial zinc based molecule for cross linking poly-acrylic acid", European Polymer Journal 47, .1338, (2011).
18 San Ping Zhao, Meng Jie Cao, Li Yan Li, Wei Lin Xu, "Synthesis and properties of biodegradable thermo and pH-sensitive poly[(N-isopropylacrylamide)-co-(methacr ylic acid) ] hydrogels", Polymer Degradation and Stability 95, 719 (2010).
19 Pierre Krausz, "Synthesis of anion exchange membranes from cellulose: Crosslinking with diiodobutane", Carbohydrate Polymers 86, .362, (2011).
20 Aiqin Hou et al., "Preparation and UV-protective properties of functional cellulose fabrics based on reactive azobenzene Schiff base derivative", Carbohydrate Polymers, 87, 84 (2012).
21 Yuezhong Wen et al., "Fast and highly efficient removal of dyes under alkaline conditions using magnetic chitosan-Fe(III) hydrogel", Water Research 45, 5200 (2011).
22 Bing-Joe Hwanga et al., "A novel crosslinking strategy for preparing poly(vinyl alcohol)-based protonconducting membranes with high sulfonation", Journal of Power Sources, 195, 2166 (2010).
23 Kohzo Ito, "Slide-ring materials using topological supramolecular architecture", Current Opinion in Solid State and Materials Science 14, 28 (2010) .
24 Bharat Indu Chaudhary et al., "Thermoreversible crosslinking of polyethylene enabled by free radical initiated functionalization with urethane nitroxyls", Polymer 51, 153 (2010).
25 Koichi Mayumi et al., "Structure and dynamics of polyrotaxane and slide-ring materials", Polymer 51, 959 (2010).
26 L.A. Wells, H. Sheardown, "Photosensitive controlled release with polyethylene glycol -anthracene modified alginate", European Journal of Pharmaceutics and Biopharmaceutics, 79(2), 304 (2011).
27 Huaming Li et al., "Phenylboronate-diol crosslinked polymer gels with reversible sol-gel transition", Polymer 52, 4268 (2011).
28 Zeng-Ying Qiao et al., "Multi-responsive nanogels containing motifs of ortho ester, oligo(ethylene glycol) and disulfide linkage as carriers of hydrophobic anti-cancer drugs", Journal of Controlled Release 152, 57 (2011).
29 Brent S. Sumerlin et al., "Future perspectives and recent advances in stimuli-responsive materials", Progress in Polymer Science, 35, .278, (2010).
30 Muxun Zhao et al., "Redox-responsive nanocapsules for intracellular protein delivery", Biomaterials 32, 5223 (2011).
31 Daniel S. Kohane et al., "Hydrogels in drug delivery: Progress and challenges", Polymer, 49, 1993 (2008).
32 M. Monier et al., "Synthesis and characterization of photo-crosslinkable hydrogel membranes based on modified chitosan", Polymer, 51, 1002 (2010).
33 Mohammad Imani et al., "Synthesis and preparation of biodegradable and visible light crosslinkable unsaturated fumaratebased networks for biomedical applications", Polym. Adv. Technol., 19(9), 1199 (2008).
34 A.A. Broekhuis., "Polymers for enhanced oil recovery: A paradigm for structure- property relationship in aqueous solution", Progress in Polymer Science, 36, 1558 (2011).
35 Hyun-Joong Kim et al., "UV-curable low surface energy fluorinated polycarbonatebased polyurethane dispersion", Journal of Colloid and Interface Science, 362, 274 (2011).
36 Shuibo Hua, Haizhen Mac, Xun Li, Huixia Yang, Aiqin Wanga," pH-sensitive sodium alginate/poly(vinyl alcohol) hydrogel beads prepared by combined $Ca^{2+}$ crosslinking and freeze-thawing cycles for controlled release of diclofenac sodium", International Journal of Biological Macromolecules, 46, 517 (2010).
37 Daniel S. Kohane et al., "Hydrogels in drug delivery: Progress and challenges", Polymer, 49, 1993 (2008).
38 Fengxian Qiu et al., "UV-curable waterborne polyurethane-acrylate: preparation, characterization and properties", Progress in Organic Coatings 73, 47 (2012).
39 Augustin T. Chen et al., Polyurethane coatings for metal and plastic substrates, Olin Corp.
40 Jason A. Burdick et al., "Hyaluronic Acid Hydrogels for Biomedical Applications", Adv. Mater. 23, 41 (2011).
41 Miqin Zhang et al., Chitosan-based hydrogels for controlled, localized drug delivery, Advanced Drug Delivery Reviews 62, 83 (2010).
42 http://www.pexassociation.net
43 N. Sheikh et al., A study on the swelling behavior of poly(acrylic acid) hydrogels obtained by electron beam crosslinking, Radiation Physics and Chemistry 79, 735 (2010).
44 Riccardo A.A. Muzzarelli, "Genipincrosslinked chitosan hydrogels as biomedical and pharmaceutical aids", Carbohydrate Polymers 77, 1 (2009).
45 Shinzo Yamashita et al., "Handbook of crosslinking agents", Taiseisha Inc., 703 (1981).
46 C.V.L. Giosafatto et al., "Microbial transglutaminase-mediated modification of ovalbumin", Food Hydrocolloids, 26, 261 (2012) .
47 Motoichi Kurisawa, "The role of stiffness of gelatine-hydroxyphenylpropionic acid hydrogels formed by enzyme-mediated crosslinking on the differentiation of human, Biomaterials 31, 8608 (2010).
48 Shantha Lakshmi Kosaraju et al., "Naturally crosslinked gelatin gels with modified material properties"' Food Research International 43, 2385 (2010).
49 Ahmed O. Elzoghby, Wael S. Abo El-Fotoh, Nazik A. Elgindy, "Caseinbased formulations as promising controlled release drug delivery systems", Journal of Controlled Release 153, 206(2011).
50 Xiaoqing Zhang et al., "Chemical Cross- Linking Gelatin with Natural Phenolic Compounds as Studied by High- Resolution NMR Spectroscopy", Biomacromolecules, 11(4), 1125 (2010).
51 Daniel Lopez,"Crosslinking of poly(vinyl alcohol) using functionalized gold nanoparticles", European Polymer Journal 46, 2099 (2010).
52 Shanjun Gao, Jinming Guo, Katsuyoshi Nishinari,"Thermoreversible konjac glucomannan gel crosslinked by borax", Carbohydrate Polymers 72, 315 (2008).
53 Shanfeng Wang et al., "Methacrylpolyhedral oligomeric silsesquioxane as a crosslinker for expediting photocrosslinking of Poly(propylene fumarate): Material properties and bone cell behavior", Polymer 52, 2827 (2011).
54 Binyang Du et al., "Preparation and characterization of thermosensitive organiceinorganic hybrid microgels with functional Fe3O4 nanoparticles as crosslinker", Polymer 52, 172 (2011).
55 Elena Loizou et al., "Structural Effects of Crosslinking a Biopolymer Hydrogel Derived from Marine Mussel Adhesive Protein", Macromol. Biosci. 6, 711 (2006).
56 Dezhen Wu et al., "The chemistry involved in the loading of silver(I) into poly(amic acid) via ion exchange: A metal-ion-induced crosslinking behavior", Polymer 50, 845 (2009).
57 Tomohiro Kawaguchi et al., "Mechanical properties of denture base resin cross-linked with methacrylated dendrimer", dental materials 27, 755 (2011).
58 Kiyoshi Yamauchi et al., "Drug Release from Hydrogel Containing Albumin as Crosslinker", Journal of Bioscience and Bioengineering , 100(5), 551 (2005).
59 Byung Kyu Kim et al., "Synthesis and characterizations of waterborne polyurethane-silica hybrids using sol-gel process", Colloids and Surfaces A: Physicochemical and Engineering Aspects, 302(1-3), 559 (2007).