Browse > Article
http://dx.doi.org/10.12925/jkocs.2010.27.4.16

Effects of Cosmetic Pigments on the Bactericidal Activities of Parabens  

Cho, Wan-Goo (Depart. of Basic Medical Science, College of Alternative Medicine, Jeonju University)
Lee, Young-Hwa (Institute of Fusion Technology, Hoseo University)
Hwang, Seong-Jin (Cosmetic R&D Center, LG H&H Ltd.)
Publication Information
Journal of the Korean Applied Science and Technology / v.27, no.4, 2010 , pp. 501-507 More about this Journal
Abstract
In this study, we evaluate the anti-microbiological activity of paraben in eye shadows that are composed of pigments and oil binders using various analytical methods and microbiological tests. Paraben does not show the microbiological activity properly when it was used with Nylon SP$^{(R)}$ 10, Talc RF SSA$^{(R)}$, OMC Talc AS$^{(R)}$ and $BaSO_4$. In the test of fungi, Nylon SP$^{(R)}$ 10 causes the decrease of microbiological activity regardless of the type of oil binders. The pigment of Mango violet also causes the decrease of microbiological activity when ester oil binder was used. Regardless of the type of oil binder, samples containing nylon SP 10, 0.15% of methyl paraben and 0.05% of propyl paraben had not been able to maintain microbiological activity only if the concentration of parabens were increased. Trace amounts of metal ions present in pigments reduced the activity of preservatives by inactivation of hydroxyl group of paraben. It is thought that swollen nylon SP 10 in ester oil increase the absorption or interaction of parabens and swollen nylon powder causes the inactivation of paraben.
Keywords
pigment; methyl paraben; inactivation; nylon powder;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 D. N. Entrekin, Relation of pH to preservative effectiveness, J. Pharm. Sci., 50, 743 (1961).   DOI
2 A. D. Russel, Bacterial adaptation and resistance to antiseptics, disinfectants and preservatives is not new, J. Hosp. Infect., 57, 97 (2004).   DOI   ScienceOn
3 H. S. Kim, K. W. Cho, and D. K. Lee, A study on the antimicrobial activity and prevervative effect of tiamine dilauryl sulfate in cosmetics, J. Kor. Oil Chem.Soc., 22(3), 212 (2005).
4 D. Coates and G. Richardson, Relationships between estimates of binding of antimicrobial agents by macromolecules, based on physiochemical and microbiological data: Benzoic acid and a nonionic surfactant, J. Appl. Bacterial., 36, 257 (1973).   DOI
5 R. A. Anderson and C. E . Chow, The distribution and activity of benzoic acid in some emulsified systems, J. Soc. Cosmet. Chem., 18, 207 (1966).
6 C. W. Bruch, Cosmetics: Sterility vs. microbial control, Am. Perfumer and Cosmetics, 86, 45 (1971).
7 M. S. Parker, Microbiologically acceptable cosmetic, Am. Perfumer and Cosmetics 86, 35 (1971).
8 I. R. Gucklhorn, Cosmetic microbiology, Manufacturing Chemist and Aerosol News, 2, 3 (1968).
9 D. Coates and G. Richardson, Relationships between estimates of binding of antimicrobial agents by macromolecules, based on physiochemical and microbiological data: Benzoic acid and a nonionic surfactant, J. Appl. Bacteriol., 3(6), 257 (1973).
10 S. M. Blaug and S. S. Ahsan, Interaction of parabens with nonionic macromolecules, J. Pharm. Sci., 50, 441 (1961).   DOI
11 R. T. Yousef, M. A. EI-Nakeeb, and S. Salama, Effect of some pharmaceutical materials on the bactericidal activities of preservatives, Cand. J. of Pharm. Sci., 8, 54 (1973).
12 T. Sakamoto, M. Yanagi, S. Fukusima, and T. Mitsui, Effects of some cosmetic pigments on the bactericidal activities of preservatives, J. Soc. Cosmet. Chem., 38, 83 (1987).