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http://dx.doi.org/10.12925/jkocs.2009.26.2.11

Anti-wrinkle Effect of Ligularia stenocephala  

Roh, Eon-Joo (Department of Health Sciences, Graduate School, Hanyang University)
Kim, Yoon-Shin (Department of Health Sciences, Graduate School, Hanyang University)
Kim, Beung-Gwan (Department of Health Sciences, Graduate School, Hanyang University)
Publication Information
Journal of the Korean Applied Science and Technology / v.26, no.2, 2009 , pp. 186-190 More about this Journal
Abstract
In the previous study, we reported the antioxidative activity and inhibition of melanogenesis of Ligularia stenocephala extracts. In this study, inhibitory effect on elastase and production type I procollagen were investigated. The compounds which was investigated were 4-hydroxyacetophenone, vanillin, chlorogenic acid, caffeic acid isolated from Ligularia stenocephala. They were slightly mild on elastase inhibition activity but 4-hydroxyacetophenone, vanillin exhibited good inhibition activity on collagen production. These results suggest that Ligularia stenocephala may have potential as an anti-aging ingredient in cosmetics.
Keywords
Ligularia stenocephala; elastase; procollagen;
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1 W. Meinhard, T. B. Iliana, N. Lale, M. Wenjian, A. S. Lars, R. W. Ziba, S. Jutta, and S. K. Karin, Solar UV irradiation and dermal photoaging, J. Photochem. Photobio. B., 63, 41, 2001   DOI   ScienceOn
2 Mosmann T. Rapid colorimetric assay for the cellular growth and survival: application to proliferation and cytotoxic assay. J Immun Methods 65:55, 1983   DOI   ScienceOn
3 A. M. Klingman and R. M. Laver, Cutaneous aging: the differences between intrinsic aging and photoaging, J. Cutan Aging Cosmet. Dermatol., 1, 5, 1988
4 I. Y. Song, Effects of electrical stimulation on collagen synthesis and type1 collagen mRNA and TGF-$\beta$1 mRNA expression in the skin, doctor's thesis, KEIMYUNG University, 2004
5 A. Oikarinen, The aging of skin: chronoaging versus photoaging, Photodermatol.Photoimmunol. Photomed, 7, 3, 1990   PUBMED
6 Cho, Jong Un; Kim, Chang Jin; Lee, Hyang Beom; Lim, Chi Hwan. Extract of Ligularia stenocephala with weed-killing activity. Korea Research Institute of Bioscience and Biotechnology, S. Korea. Repub. Korean Kongkae Taeho Kongbo, 2004