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http://dx.doi.org/10.12925/jkocs.2005.22.3.2

A Study on the Antimicrobial Activity and Preservative Effect of Thiamine Dilauryl Sulfate in Cosmetics  

Lee, Dong-Kyu (Department of Industrial Chemical Engineering, Chungbuk National University)
Kim, Hyuk-Soo (Research Institute of Dr.Chung's Food Co.)
Cho, Kyung-Whan (Research Institute of Dr.Chung's Food Co.)
Publication Information
Journal of the Korean Applied Science and Technology / v.22, no.3, 2005 , pp. 212-218 More about this Journal
Abstract
Most of cosmetics are emulsion products that contain the source of nutrition vegetable oil, mineral oil, natural extract and carbohydrate etc. There are many possibilities to be contaminated by microbials. We investigated the effect of antimicrobial and minimum inhibitory concentration(MIC) with thiamine dilauryl sulfate(TDS), which was prepared to use cosmetic lotion formulation. Staphylococcus aureus(S. aureus) and Escherichia col(E. coli) were used as test organism. MIC value of TDS was determined aganist microorganism for the growth inhibition by concentration of TDS. From the MIC results, antimicrobial effect of TDS was generally more effective to gram positive than gram negative. Antimicrobial effect with pH value against some microorganism appeared in the following order : pH 5 > pH 6 > pH 7. It showed strong antimicrobial activities against S. aureus, and weak antimicrobial activities against E. coli. If it was possible to determine the formulations with TDS, it would be effective to reduce the artificial preservatives.
Keywords
thiamine dilauryl sulfate(TDS); cosmetics; antimicrobial activity; preservative Effect;
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